Chung Kwang Hyun, Lee Sang Hyub, Park Jin Myung, Lee Jae Min, Shin Cheol Min, Ahn Sang Hoon, Park Do Joong, Kim Hyung-Ho, Ryu Ji Kon, Kim Yong-Tae
Division of Gastroenterology, Department of Internal Medicine and Liver Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, 101, Daehak-ro, Jongno-gu, Seoul, 110-744, Korea.
Department of Internal Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-Do, 463-707, Korea.
Gastric Cancer. 2016 Jan;19(1):280-6. doi: 10.1007/s10120-014-0450-3. Epub 2014 Dec 12.
A partially covered self-expandable metallic stent (PCSEMS) is of proven benefit in palliation of unresectable or inoperable malignant gastric outlet obstruction. However, its use in patients with benign anastomotic stricture after laparoscopy-assisted gastrectomy (LAG) is not well established.
Patients who between May 2007 and June 2012 underwent PCSEMS placement for management of benign gastrointestinal obstruction after LAG were included in this retrospective analysis. The primary outcomes were the technical success and clinical success of the PCSEMS. The secondary outcomes were procedure-related complications and PCSEMS dysfunction.
Eleven patients (six women, five men, mean age 53.5 years, range 15-76 years) underwent successful placement of a PCSEMS for management of benign anastomotic strictures after LAG and were followed-up for a mean of 20.6 months (range 7.9-55.6 months). The mean gastric outlet obstruction scoring system (GOOSS) score was 0.36 before PCSEMS placement and 1.55 (p = 0.010) 24-48 h after PCSEMS placement. All of the patients were able to tolerate a solid diet (GOOSS score 3) after 1 week. There were no major or minor procedure-related complications. Stent dysfunction occurred in four patients (three distal migrations, one proximal migration), and stent removal was successful in all of the remaining patients after a mean of 2.0 months (1.1-3.0 months). Obstructive symptoms recurred in two patients (one after proximal migration, one after stent removal) and were treated successfully with PCSEMS reinsertion and balloon dilation.
A PCSEMS may be a feasible and effective option for management of benign anastomotic strictures after LAG which could avoid secondary surgery.
部分覆盖的自膨式金属支架(PCSEMS)已被证实对不可切除或无法手术的恶性胃出口梗阻的姑息治疗有益。然而,其在腹腔镜辅助胃切除术后(LAG)良性吻合口狭窄患者中的应用尚未明确。
本回顾性分析纳入了2007年5月至2012年6月期间因LAG后良性胃肠道梗阻而接受PCSEMS置入的患者。主要结局是PCSEMS的技术成功和临床成功。次要结局是与手术相关的并发症和PCSEMS功能障碍。
11例患者(6例女性,5例男性,平均年龄53.5岁,范围15 - 76岁)成功置入PCSEMS以处理LAG后的良性吻合口狭窄,并接受了平均20.6个月(范围7.9 - 55.6个月)的随访。PCSEMS置入前胃出口梗阻评分系统(GOOSS)的平均评分为0.36,置入后24 - 48小时为1.55(p = 0.010)。所有患者在1周后均能耐受固体食物(GOOSS评分为3)。没有发生与手术相关的重大或轻微并发症。4例患者出现支架功能障碍(3例远端移位,1例近端移位),其余所有患者在平均2.0个月(1.1 - 3.0个月)后成功取出支架。2例患者出现梗阻症状复发(1例在近端移位后,1例在支架取出后),经再次置入PCSEMS和球囊扩张成功治疗。
PCSEMS可能是处理LAG后良性吻合口狭窄的一种可行且有效的选择,可避免二次手术。