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与门诊诊所后续药剂师进行的用药核对相关的用药差异。

Medication discrepancies associated with subsequent pharmacist-performed medication reconciliations in an ambulatory clinic.

作者信息

Philbrick Ann M, Harris Ila M, Schommer Jon C, Fallert Christopher J

出版信息

J Am Pharm Assoc (2003). 2015 Jan-Feb;55(1):77-80. doi: 10.1331/JAPhA.2015.13160.

DOI:10.1331/JAPhA.2015.13160
PMID:25504145
Abstract

OBJECTIVE

To describe the number of medication discrepancies associated with subsequent medication reconciliations by a clinical pharmacist in an ambulatory family medicine clinic and the proportion of subsequent medication reconciliation visits that were associated with hospital discharge, long-term anticoagulation management, or both.

METHODS

Data on medication reconciliations were collected over a 2-year time period in an ambulatory family medicine clinic for patients taking 10 or more medications.

RESULTS

Medication reconciliation was performed 752 times for 500 patients. A total of 5,046 discrepancies were identified, with more than one-half deemed clinically important. A mean (± SD) of 6.7 ± 4.6 discrepancies per visit (3.5 ± 3.2 clinically important) were identified. The findings showed that the distribution of total discrepancies identified by pharmacist-performed medication reconciliation was significantly different over the course of subsequent medication reconciliations. However, the distribution of clinically important discrepancies was not significantly different; important discrepancies were as likely to be found in later reconciliations as in earlier ones. As subsequent medication reconciliation visits were performed, an increasing proportion consisted of post-hospital discharge visits, long-term anticoagulation managed by a clinical pharmacist, or both.

CONCLUSION

Patients with a recent hospital discharge, on long-term anticoagulation management, or both, were more likely to have multiple sessions with a clinical pharmacist for medication reconciliation. These findings can help identify patients for whom medication reconciliation is warranted.

摘要

目的

描述在一家门诊家庭医学诊所中,临床药师进行的后续用药核对所涉及的用药差异数量,以及与出院、长期抗凝管理或两者都相关的后续用药核对就诊比例。

方法

在一家门诊家庭医学诊所,对服用10种或更多药物的患者,在2年时间内收集用药核对数据。

结果

对500名患者进行了752次用药核对。共识别出5046处差异,其中超过一半被认为具有临床重要性。每次就诊平均(±标准差)识别出6.7±4.6处差异(3.5±3.2处具有临床重要性)。研究结果表明,在后续用药核对过程中,临床药师进行的用药核对所识别出的总差异分布存在显著差异。然而,具有临床重要性的差异分布并无显著差异;在后期核对中发现重要差异的可能性与早期相同。随着后续用药核对就诊的进行,由出院后就诊、临床药师管理的长期抗凝或两者组成的就诊比例不断增加。

结论

近期出院、接受长期抗凝管理或两者兼具的患者,更有可能多次与临床药师进行用药核对。这些发现有助于确定需要进行用药核对的患者。

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