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[顿涅茨克地区功能性消化不良患者的幽门螺杆菌感染及根除率]

[Helicobacter pylori infection in patients with functional dyspepsia, eradication rates in the Donetsk region].

作者信息

Dorofeev A É, Rudenko N N, Agibalov A N, Kugler T E, Sibilev A V, Tomash O V

出版信息

Lik Sprava. 2014 Nov(11):119-22.

Abstract

We have investigated 175 patients with Rome III diagnostic criteria for functional dyspepsia. 104 (59%) patients were infected with Helicobacter pylori. Three-component (PPI + clarithromycin + amoxicillin) 7-day therapy with the addition of the probiotic was effective in 92 patients (88.4%). Dyspeptic symptoms were resolved in 37 patients with successful eradication (40%). Persistent effect for 6 months was maintained in 24 patients (26%). Eradication efficacy in eliminating of the dyspepsia symptoms was higher in epigastric pain syndrome than postprandial distress syndrome.

摘要

我们依据罗马III功能性消化不良诊断标准对175例患者进行了研究。104例(59%)患者感染幽门螺杆菌。三联疗法(质子泵抑制剂+克拉霉素+阿莫西林)联合益生菌进行7天治疗,92例患者(88.4%)有效。37例成功根除幽门螺杆菌的患者(40%)消化不良症状得到缓解。24例患者(26%)维持了6个月的持续疗效。上腹部疼痛综合征患者根除幽门螺杆菌后消除消化不良症状的疗效高于餐后不适综合征患者。

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