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[自主神经功能障碍在肠易激综合征发病机制中的作用]

[The role of autonomic dysfunction in pathogenesis of irritable bowel syndrome].

作者信息

Lebedeva M A, Karganov M Yu, Kozlova Y A, Gotovtceva G N, Tumurov D A, Gudkova A A, Guekht A B

出版信息

Patol Fiziol Eksp Ter. 2014 Jul-Sep(3):37-44.

Abstract

This article presents the results of a comparative study of autonomic disorders in patients with differernt types of irritable bowel syndrome (IBS). We used several clinical and instrumental methods, including the Veyn questionnaire, Kerdo autonomic index, skin sympathetic response and heart rate variability analysis. The results show a prevalence of sympathetic tone in all groups of patients (more pronounced in IBS with constipation), as well as an elevated stress index and decreased arterial baroreflex sensitivity. In the IBS with diarrhea group there was a reliable increase of power spectral density alvery low frequency and a lowered respiratory sinus arrhythmia.

摘要

本文介绍了不同类型肠易激综合征(IBS)患者自主神经功能紊乱的比较研究结果。我们使用了多种临床和仪器检查方法,包括韦恩问卷、凯尔多自主神经指数、皮肤交感反应和心率变异性分析。结果显示,所有患者组均存在交感神经张力增加(在便秘型IBS中更为明显),以及应激指数升高和动脉压力反射敏感性降低。腹泻型IBS组的极低频功率谱密度可靠增加,呼吸性窦性心律不齐降低。

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