Mrochuk May, ÓDochartaigh Domhnall, Chang Eddie
Department of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canada; Shock Trauma Air Rescue Society, Edmonton, Alberta, Canada.
Shock Trauma Air Rescue Society, Edmonton, Alberta, Canada.
Air Med J. 2015 Jan-Feb;34(1):37-9. doi: 10.1016/j.amj.2014.09.004.
Tranexamic acid (TXA) administration has been shown to reduce mortality in bleeding trauma patients if given in the hospital within 3 hours of injury. Its use has been theorized to be of benefit in the prehospital environment. This study evaluates the timing of TXA administration in a critical care helicopter emergency medical service (HEMS) versus that of the destination trauma hospital.
We performed a retrospective chart review of consecutive trauma patients who were given TXA during HEMS transfer. The time of injury to HEMS arrival, TXA administration, and hospital arrival was collected.
Twenty complete records were identified in which TXA was administered by HEMS: 11 scene calls and 9 interfacility transfers. The median time in minutes from the time of injury to HEMS arrival, TXA administration, and receiving hospital arrival was 90, 114, and 171, respectively, for scene calls and 134, 173, and 224, respectively, for interfacility transfers.
TXA must be administered before arrival at a trauma hospital to meet the recommendation of administration within 3 hours of injury for all patients transferred between facilities and for many patients transported from a trauma scene.
已证明,对于出血性创伤患者,若在受伤后3小时内在医院给予氨甲环酸(TXA),可降低死亡率。理论上,在院前环境中使用TXA有益。本研究评估了在重症监护直升机紧急医疗服务(HEMS)中给予TXA的时间与目的地创伤医院给予TXA的时间。
我们对在HEMS转运期间接受TXA治疗的连续创伤患者进行了回顾性病历审查。收集了受伤至HEMS到达、给予TXA以及医院到达的时间。
确定了20份完整记录,其中HEMS给予了TXA:11次现场呼叫和9次机构间转运。对于现场呼叫,从受伤到HEMS到达、给予TXA以及到达接收医院的中位时间(以分钟为单位)分别为90、114和171,对于机构间转运分别为134、173和224。
对于在各机构间转运的所有患者以及许多从创伤现场转运的患者,必须在到达创伤医院之前给予TXA,以满足在受伤后3小时内给药的建议。