Tolley Neil, Garas George, Palazzo Fausto, Prichard Alexa, Chaidas Konstantinos, Cox Jeremy, Darzi Ara, Arora Asit
Department of Otorhinolaryngology and Head & Neck Surgery, St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
Department of Endocrine and Thyroid Surgery, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
Head Neck. 2016 Apr;38 Suppl 1:E300-6. doi: 10.1002/hed.23990. Epub 2015 Jun 26.
Targeted parathyroidectomy is a popular technique for localized pathology. No single technique is established as superior. The purpose of this study was to compare robotic-assisted parathyroidectomy (RAP) with the most common approach.
This was a prospective, nonrandomized study. Fifteen consecutive patients who underwent RAP were compared to 15 matched controls undergoing focused lateral parathyroidectomy (FLP).
Biochemical cure occurred in 29 of 30 patients (97%). No major complications occurred, although there was 1 robotic conversion. RAP demonstrated a significant time reduction (R(2) = 0.436; p = .01) but took much longer to perform than FLP (119 minutes vs 34 minutes; p = .001). RAP was associated with less initial postoperative pain (p = .036) and higher satisfaction with scar cosmesis (p = .002) until 6 months. Quality of life (QOL) improved in both groups (p = .007).
RAP provides superior early cosmesis with equivalent global health improvement compared to FLP. The high cost and learning curve may preclude widespread adoption. Further evaluation is necessary to establish its clinical efficacy regarding scar cosmesis. © 2015 Wiley Periodicals, Inc. Head Neck 38: E300-E7, 2016.
靶向甲状旁腺切除术是一种针对局部病变的常用技术。目前尚无一种技术被公认为更具优势。本研究的目的是将机器人辅助甲状旁腺切除术(RAP)与最常用的方法进行比较。
这是一项前瞻性、非随机研究。将连续15例行RAP的患者与15例匹配的接受聚焦外侧甲状旁腺切除术(FLP)的对照患者进行比较。
30例患者中有29例(97%)实现生化治愈。尽管有1例转为开放手术,但未发生重大并发症。RAP显示手术时间显著缩短(R(2) = 0.436;p = .01),但手术时间仍比FLP长得多(119分钟对34分钟;p = .001)。直到术后6个月,RAP术后初期疼痛较轻(p = .036),对瘢痕美观的满意度较高(p = .002)。两组患者的生活质量(QOL)均有所改善(p = .007)。
与FLP相比,RAP在早期美观效果方面更优,对整体健康的改善相当。高成本和学习曲线可能会阻碍其广泛应用。有必要进一步评估其在瘢痕美观方面的临床疗效。© 2015威利期刊公司。《头颈》38: E300 - E7, 2016。