Hökfelt B
Acta Endocrinol Suppl (Copenh). 1978;216:67-74.
The sympathetic nervous system and the renin-angiotensin mechanism each can influence blood pressure separately but the two systems also interact functionally in various ways. There is good evidence that central catecholaminergic neurons play an essential role in the regulation of blood pressure but it may be assumed that other putative neurotransmittors such as serotonin, GABA and various peptides also participate in the central regulation of blood pressure. The secretion of renin, which catalyzes the production of angiotensin(s), is stimulated by increased sympathetic activity and circulating sympathetic amines. Dopamine seems to have an opposite effect on renin release but it is not clear whether this is due to a direct effect on the renin producing cells or an influence on sympathetic activity, centrally or peripherally.
交感神经系统和肾素-血管紧张素机制各自都能独立影响血压，但这两个系统在功能上也以多种方式相互作用。有充分证据表明，中枢儿茶酚胺能神经元在血压调节中起重要作用，但可以推测，其他假定的神经递质，如5-羟色胺、γ-氨基丁酸和各种肽类，也参与血压的中枢调节。肾素的分泌受交感神经活动增强和循环中交感胺的刺激，肾素催化血管紧张素的生成。多巴胺似乎对肾素释放有相反的作用，但尚不清楚这是由于对肾素产生细胞的直接作用，还是对中枢或外周交感神经活动的影响。
