WEILL CORNELL MEDICAL COLLEGE.
Blood. 2015 Jan 1;125(1):7-9. doi: 10.1182/blood-2014-11-609230.
In this issue of , Scheicher et al show that cyclin-dependent kinase 6 (CDK6) has a novel role in the regulation of both normal and leukemic stem cells. It acts as a transcriptional suppressor of , enabling it to control both normal and leukemic stem cell activation.
本期 ,Scheicher 等人表明细胞周期蛋白依赖性激酶 6(CDK6)在正常和白血病干细胞的调控中具有新的作用。它作为 的转录抑制因子发挥作用,使其能够控制正常和白血病干细胞的激活。