Emory University Hospital, Department of Radiology and Imaging Sciences, 1364 Clifton Rd, NE, Atlanta, GA, 30322.
Prog Cardiovasc Dis. 2015 May-Jun;57(6):579-87. doi: 10.1016/j.pcad.2014.12.006. Epub 2014 Dec 31.
The American Society of Nuclear Cardiology has recently published documents that encourage laboratories to take all the appropriate steps to greatly decrease patient radiation dose and has set the goal of 50% of all myocardial perfusion studies performed with an associated radiation exposure of 9mSv by 2014. In the present work, a description of the major software techniques readily available to shorten procedure time and decrease injected activity is presented. Particularly new reconstruction methods and their ability to include means for resolution recovery and noise regularization are described. The use of these improved reconstruction algorithms results in a consistent reduction in acquisition time, injected activity and consequently in the radiation dose absorbed by the patient. The clinical implications to the use of these techniques are also described in terms of maintained and even improved study quality, accuracy and sensitivity for the detection of heart disease.
美国核医学学会最近发布的文件鼓励实验室采取一切适当措施，大幅降低患者的辐射剂量，并设定了到 2014 年所有心肌灌注研究的 50%都以 9mSv 为相关辐射暴露量的目标。在本工作中，描述了可用于缩短检查时间和减少注射活动的主要软件技术。特别描述了新的重建方法及其包含分辨率恢复和噪声正则化手段的能力。使用这些改进的重建算法可一致减少采集时间、注射活动，从而减少患者吸收的辐射剂量。还从保持甚至提高检测心脏病的研究质量、准确性和灵敏度的角度，描述了这些技术的临床意义。
