阴茎头麻风结节性红斑：常见疾病的不寻常表现。
Erythema nodosum leprosum on glans penis: unusual manifestation of common disease.
作者信息
Kothiwala Sunil Kumar, Khandpur Sujay, Singh Manoj Kumar, Durgapal Prashant
机构信息
Department of Dermatology and Venereology, All India Institute of Medical Science, New Delhi, India.
Department of Pathology, All India Institute of Medical Science, New Delhi, India.
出版信息
Int J Dermatol. 2015 Sep;54(9):1060-3. doi: 10.1111/ijd.12772. Epub 2014 Dec 29.
BACKGROUND
Erythema nodosum leprosum (ENL) classically presents as tender evanescent skin nodules involving extremities, trunk, and face but may appear at any site. Mucosal involvement in ENL is uncommon, and its occurrence over glans is extremely rare.
METHOD
We describe two interesting cases of ENL involving the glans penis and prepuce with different presentations.
RESULT
The first case had lepromatous leprosy with ENL with involvement of the glans penis in the form of a painful ulcer with necrotic slough. The second case had borderline lepromatous leprosy with ENL with involvement of glans in the form of a single painful nodule. Histopathology showed features of ENL, and Ziehl-Neelsen staining showed numerous acid fast bacilli.
CONCLUSION
We should be aware of genital involvement of ENL, which is a rare presentation and needs to be differentiated from other conditions requiring a different management approach.
背景
结节性红斑型麻风（ENL）通常表现为累及四肢、躯干和面部的压痛性短暂性皮肤结节，但可出现在任何部位。ENL累及黏膜并不常见，而发生于龟头的情况极为罕见。
方法
我们描述了两例累及阴茎头和包皮且表现各异的有趣的ENL病例。
结果
第一例为瘤型麻风伴ENL，阴茎头受累表现为疼痛性溃疡伴坏死性痂皮。第二例为界线类偏瘤型麻风伴ENL，龟头受累表现为单个疼痛性结节。组织病理学显示ENL特征，齐-尼氏染色显示大量抗酸杆菌。
结论
我们应意识到ENL累及生殖器的情况，这是一种罕见表现，需要与其他需要不同管理方法的疾病相鉴别。
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