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在巴西利亚早期类风湿性关节炎队列研究中随访的女性患者性功能障碍患病率。

Prevalence of sexual dysfunction among female patients followed in a Brasília Cohort of early rheumatoid arthritis.

作者信息

Costa Thaís Ferreira, Silva Carolina Rocha, Muniz Luciana Feitosa, Mota Licia Maria Henrique da

机构信息

Serviço de Reumatologia, Hospital Universitário de Brasília, Universidade de Brasília, Brasília, DF, Brasil.

Serviço de Reumatologia, Hospital Universitário de Brasília, Universidade de Brasília, Brasília, DF, Brasil.

出版信息

Rev Bras Reumatol. 2015 Mar-Apr;55(2):123-32. doi: 10.1016/j.rbr.2014.10.006. Epub 2014 Nov 25.

Abstract

OBJECTIVE

To determine the prevalence of sexual dysfunction in women diagnosed with early rheumatoid arthritis (RA) (less than one year of symptoms at the time of diagnosis), as well as to evaluate the possible association between sexual dysfunction with AR activity and functional disability.

METHODS

Cross-sectional study assessing women diagnosed with early RA, accompanied per protocol in the Brasilia Cohort, Hospital Universitário de Brasília. Demographics, disease activity index (Disease Activity Score 28 - DAS 28) and functional disability questionnaire (Health Assessment Questionnaire - HAQ), were obtained by direct interviews. The Female Sexual Function Index (FSFI) was used, questionnaire which contains 19 items that assess six domains: sexual desire, sexual arousal, vaginal lubrication, orgasm, sexual satisfaction and pain.

RESULTS

68 patients studied, of whom 54 (79.4%) reported sexual activity in the last four weeks. The participants were 49.7±13.7 (mean±SD) years old and the majority were married (61.4%). The mean DAS 28 was 3.6±1.5 and the mean HAQ was 0.7. The prevalence of sexual dysfunction (FSFI ≤26) was 79.6%. There was no association of disease activity or of functional disability with the occurrence of sexual dysfunction in the female patients evaluated.

CONCLUSION

The prevalence of sexual dysfunction found in this study was higher than that reported in the literature in healthy women. A knowledge of the extent of the problem is needed to provide adequate therapeutic options for these patients.

摘要

目的

确定被诊断为早期类风湿关节炎(RA)(诊断时症状出现少于一年)的女性性功能障碍的患病率,并评估性功能障碍与类风湿关节炎活动及功能残疾之间可能存在的关联。

方法

在巴西利亚大学医院巴西利亚队列中,按照方案对被诊断为早期类风湿关节炎的女性进行横断面研究。通过直接访谈获取人口统计学信息、疾病活动指数(疾病活动评分28 - DAS 28)和功能残疾问卷(健康评估问卷 - HAQ)。使用女性性功能指数(FSFI)问卷,该问卷包含19个项目,评估六个领域:性欲、性唤起、阴道润滑、性高潮、性满意度和疼痛。

结果

研究了68名患者,其中54名(79.4%)报告在过去四周内有性活动。参与者年龄为49.7±13.7(均值±标准差)岁,大多数已婚(61.4%)。平均DAS 28为3.6±1.5,平均HAQ为0.7。性功能障碍(FSFI≤26)的患病率为79.6%。在所评估的女性患者中,疾病活动或功能残疾与性功能障碍的发生之间没有关联。

结论

本研究中发现的性功能障碍患病率高于文献报道的健康女性患病率。需要了解该问题的严重程度,以便为这些患者提供适当的治疗选择。

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