[Fracture healing under intramedullary insertion of wires with hydroxyapatite coating].

AIM

To study morphological features of the bone formation process in consolidation of fractures of long tubular bones in conditions of intramedullary wires insertion with bioactive calcium-phosphate coating of hydroxyapatite.

MATERIALS AND METHODS

In experimental study in dogs was simulated open comminuted tibia fracture and performed intramedullary insertion of wires with hydroxyapatite coating. Using light and electron microscopy, using X-ray electron microprobe microanalyses were studied bone regenerates in 14-360 days after surgery.

RESULTS

It was found that around wires there is a formation of an area of active reparative bone formation and angiogenesis, bone shaped case with the properties of the conductor and inducer of osteogenesis. Fracture consolidation is carried out in the early stages of the primary type without formation of cartilage and connective tissue in the bone adhesion.

CONCLUSION

Study results testify that intramedullary wires with hydroxyapatite coating positively influence on the process and intensity of reparative bone formation in fracture healing.