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先天性心脏病成人患者的杂交分支肺动脉支架置入术。

Hybrid branch pulmonary artery stent placement in adults with congenital heart disease.

作者信息

Lynch Winston, Boekholdt S Mathijs, Hazekamp Mark G, de Winter Robbert J, Koolbergen David R

机构信息

Department of Cardiothoracic Surgery, Academic Medical Centre, Amsterdam, Netherlands.

Department of Cardiology Academic Medical Centre, Amsterdam, Netherlands.

出版信息

Interact Cardiovasc Thorac Surg. 2015 Apr;20(4):499-503. doi: 10.1093/icvts/ivu435. Epub 2015 Jan 6.

Abstract

OBJECTIVES

Valuable treatment modalities for branch pulmonary artery (BPA) stenoses are surgical patch angioplasty, percutaneous BPA stenting and hybrid stent placement. The purpose of this study was to report our institutional experience with hybrid stent placement to relieve BPA stenoses.

METHODS

Between August 2007 and May 2014, 7 adults (5 females) with congenital heart disease (CHD) had elective intraoperative BPA stent placement. All 7 patients had undergone previous surgery [6 tetralogy of Fallot repairs and 1 arterial switch operation for transposition of the great arteries (TGAs)]. A total of 7 stents (4 right pulmonary artery, 3 left pulmonary artery) were implanted under direct vision, concomitant with a pulmonary homograft implantation (tetralogy of Fallot patients), or because percutaneous stenting was not feasible (TGA patient). Retrospective analysis of clinical data, procedural details and outcomes was performed.

RESULTS

Overall, the mean age was 35 ± 7.2 years. Stent implantation was successful in all procedures. The mean postinflation stent diameter was 13.3 ± 2.0 mm. No stent migration, fracture, stent thrombosis, reintervention or deaths occurred. In 1 case the procedure was complicated by a right pulmonary artery tear just distal to the stent which was repaired by surgical patch angioplasty. At a mean follow-up of 55.6 ± 26 months no patient required catheter reintervention or surgery. Echocardiography (mean follow-up 47.1 ± 22 months), MRI (mean follow-up 43.8 ± 37 months) and CT data (mean follow-up 14.8 ± 10 months) demonstrate a BPA diameter increment from a mean 5.57 ± 2.29 to 10.71 ± 2.56 mm.

CONCLUSIONS

Hybrid intraoperative BPA stent placement is safe and effective and can be used as an alternative for surgical patch angioplasty or if percutaneous BPA stenting is not feasible. Short- to mid-term results are good.

摘要

目的

对于分支肺动脉(BPA)狭窄,有价值的治疗方式包括外科补片血管成形术、经皮BPA支架置入术和杂交支架置入术。本研究的目的是报告我们机构采用杂交支架置入术缓解BPA狭窄的经验。

方法

2007年8月至2014年5月期间,7例患有先天性心脏病(CHD)的成人(5例女性)接受了择期术中BPA支架置入术。所有7例患者均曾接受过手术[6例法洛四联症修复术和1例大动脉转位(TGA)的动脉调转手术]。在直视下共植入了7枚支架(4枚右肺动脉支架,3枚左肺动脉支架),同时进行了肺动脉同种异体移植植入术(法洛四联症患者),或因经皮支架置入不可行(TGA患者)。对临床资料、手术细节和结果进行了回顾性分析。

结果

总体而言,平均年龄为35±7.2岁。所有手术中支架植入均成功。球囊扩张后支架平均直径为13.3±2.0毫米。未发生支架移位、断裂、支架血栓形成、再次干预或死亡。1例手术出现并发症,支架远端的右肺动脉撕裂,通过外科补片血管成形术修复。平均随访55.6±26个月时,无患者需要导管再次干预或手术。超声心动图(平均随访47.1±22个月)、MRI(平均随访43.8±37个月)和CT数据(平均随访14.8±10个月)显示,BPA直径从平均5.57±2.29毫米增加到10.71±2.56毫米。

结论

杂交术中BPA支架置入术安全有效,可作为外科补片血管成形术的替代方法,或在经皮BPA支架置入不可行时使用。短期至中期结果良好。

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