解析淀粉样纤维的结构多态性。

Unraveling structural polymorphism of amyloid fibers.

机构信息

Department of Life Sciences, Sir Ernst Chain Building, South Kensington Campus, Imperial College London, London SW7 2AZ, UK.

出版信息

Structure. 2015 Jan 6;23(1):10-11. doi: 10.1016/j.str.2014.12.005.

DOI:10.1016/j.str.2014.12.005

PMID:25565103

Abstract

Amyloid fibers are self-assembling cross β sheet structures whose overall molecular architecture is highly variable. In this issue of Structure, Torreira and colleagues use electron microscopy to resolve ultrastructural polymorphisms of RepA-WH1 amyloids.

摘要

淀粉样纤维是自组装的交叉 β 片层结构，其整体分子结构高度可变。在本期结构杂志中，Torreira 及其同事使用电子显微镜解析了 RepA-WH1 淀粉样蛋白的超微结构多态性。