Horita A
Adv Exp Med Biol. 1978;97:171-85. doi: 10.1007/978-1-4684-7793-1_10.
This review has attempted to convey the idea that the current concepts of psychotropic drug actions are based largely around the monoamine transmitter systems. Several of the hypotheses which implicate abnormalities of these systems as factors involved in the aging brain are discussed. It is suggested that the current lack of specific geriatric psychotropic agents is in part a reflection of our ignorance of the neurochemical basis of the aging process.
本综述试图传达这样一种观点,即目前关于精神药物作用的概念在很大程度上是围绕单胺递质系统展开的。文中讨论了一些将这些系统的异常视为与大脑衰老相关因素的假说。有人认为,目前缺乏特定的老年精神药物,部分反映了我们对衰老过程的神经化学基础的无知。