Jennings Victoria Caroline Elizabeth, Williams Lisa, Henson Sophie
Department of Gastroenterology, Singleton Hospital, Swansea, UK.
BMJ Case Rep. 2015 Jan 9;2015:bcr2013203005. doi: 10.1136/bcr-2013-203005.
An 11-year-old girl was referred to oral medicine with persistent facial swelling. She was diagnosed with orofacial granulomatosis (OFG) and was treated conservatively for 7 years, with no evidence of systemic illness. Aged 17 she re-presented with a flare up of her OFG, watery diarrhoea and fluctuating febrile episodes. Inflammatory markers were raised and an MR enterogram revealed terminal ileal Crohn's disease. This case highlights that OFG may precede the onset of intestinal Crohn's disease.
一名11岁女孩因面部持续肿胀被转诊至口腔医学科。她被诊断为口面部肉芽肿病(OFG),并接受了7年的保守治疗,没有全身疾病的迹象。17岁时,她因OFG复发、水样腹泻和发热波动再次就诊。炎症指标升高,磁共振小肠造影显示末端回肠克罗恩病。该病例表明,OFG可能先于肠道克罗恩病发病。