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[阵发性心房颤动的介入治疗:哪种消融方法最佳?]

[Interventional treatment for paroxysmal atrial fibrillation : which is the optimal ablation approach?].

作者信息

Sultan A, Lüker J, Plenge T, Steven D

机构信息

III. Med. Klinik, Abteilung für Elektrophysiologie, Herzzentrum der Universität zu Köln, Kerpenerstr. 67, 50937, Köln, Deutschland.

出版信息

Herz. 2015 Feb;40(1):25-30. doi: 10.1007/s00059-014-4195-x.

Abstract

Atrial fibrillation is one of the most common arrhythmias and effects probably more than 35 million people worldwide. The incidence in patients older than 70 years of age is as high as 10%. One can expect that according to our demographic development this entity will be increasingly important within the next years and decades. Along with the well know and established but at the same time limited opportunities of pharmacological treatment option of this arrhythmia, catheter ablation has evolved as a safe and effective treatment option. Electrical isolation of the pulmonary vein remains the standard of care and results in success rates as high as 80% using modern ablation strategies. Optimization of procedural and ablation techniques has lead to this high success rates. Different energy sources are available, such as radiofrequency, cryoenergy and laser are widely used today to treat patients with symptomatic atrial fibrillation. PV isolation using a so called "single-shot" ablation approach has shown to be effective with a reduced requirement of periprocedural resources and therefore resulting in wider application of this treatment not only in specialized electrophysiological centers. The rapid development in this field leads to the question which approach can be used as the most likely to result in the highest success and least complication rates. This question will be addressed in the following manuscript.

摘要

心房颤动是最常见的心律失常之一,全球可能有超过3500万人受其影响。70岁以上患者的发病率高达10%。可以预计,根据我们的人口发展趋势,在未来几年和几十年内,这一疾病将变得越来越重要。除了这种心律失常的药物治疗选择众所周知且已确立,但同时也存在局限性之外,导管消融已发展成为一种安全有效的治疗选择。肺静脉电隔离仍然是治疗的标准方法,采用现代消融策略的成功率高达80%。手术和消融技术的优化带来了如此高的成功率。目前有多种能量来源可供使用,如射频、冷冻能量和激光,如今广泛用于治疗有症状的心房颤动患者。使用所谓“单次”消融方法进行肺静脉隔离已被证明是有效的,减少了围手术期资源的需求,因此这种治疗方法不仅在专业电生理中心得到更广泛应用。该领域的快速发展引发了一个问题,即哪种方法最有可能带来最高的成功率和最低的并发症发生率。以下手稿将探讨这个问题。

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