Chen Yi-Jen, Chen Chia-Hsin, Wang Chao-Ling, Huang Mao-Hsiung, Chen Tien-Wen, Lee Chia-Ling
Department of Physical Medicine and Rehabilitation, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan; Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Department of Physical Medicine and Rehabilitation, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan; Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Physical Medicine and Rehabilitation, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Arch Phys Med Rehabil. 2015 May;96(5):837-44. doi: 10.1016/j.apmr.2015.01.004. Epub 2015 Jan 13.
To determine the association between the severity of femoral condylar cartilage erosion resulting from knee osteoarthritis (OA) by an ultrasonographic grading system and the clinical symptoms and functions.
Cross-sectional study.
A tertiary center.
Participants (N=101) with and without subjective complaints of knee discomfort were consecutively enrolled. Patients who had ever received knee arthroplasty, who had inflammatory arthritis, and whose knee flexion range of motion was <90° were excluded. A total of 194 knees were evaluated.
Not applicable.
A semiquantitative ultrasonographic grading system was used to evaluate the severity of femoral condylar cartilage erosion. The clinical symptoms and functions were evaluated with the visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Lequesne index. The association of the VAS/WOMAC/Lequesne index with the ultrasonographic grading was assessed.
Positive linear associations were found between the ultrasonographic grading and the following: the VAS and the total scores and pain subscales of both the Lequesne index and WOMAC. Multivariate logistic regression analysis revealed grade-dependent association between VAS and ultrasonographic grading after adjusting for age, sex, and body mass index. The WOMAC and Lequesne index scores were associated with the ultrasonographic grading in more severe degrees, particularly in the pain subscales.
This semiquantitative ultrasonographic grading system may well reflect the clinical symptoms and functions related to knee OA as evaluated by the VAS, WOMAC, and Lequesne index. This method provides a more comprehensive description and measurement of knee OA.
通过超声分级系统确定膝关节骨关节炎（OA）导致的股骨髁软骨侵蚀严重程度与临床症状及功能之间的关联。
横断面研究。
三级医疗中心。
连续纳入有或无膝关节不适主观症状的参与者（N = 101）。排除曾接受膝关节置换术、患有炎性关节炎以及膝关节屈曲活动范围<90°的患者。共评估了194个膝关节。
不适用。
采用半定量超声分级系统评估股骨髁软骨侵蚀的严重程度。采用视觉模拟量表（VAS）、西安大略和麦克马斯特大学骨关节炎指数（WOMAC）以及Lequesne指数评估临床症状和功能。评估VAS/WOMAC/Lequesne指数与超声分级之间的关联。
超声分级与以下指标之间存在正线性关联：VAS以及Lequesne指数和WOMAC的总分及疼痛子量表。多因素逻辑回归分析显示，在调整年龄、性别和体重指数后，VAS与超声分级之间存在分级依赖性关联。WOMAC和Lequesne指数评分与超声分级在更严重程度上相关，尤其是在疼痛子量表中。
这种半定量超声分级系统可能很好地反映了通过VAS、WOMAC和Lequesne指数评估的与膝关节OA相关的临床症状和功能。该方法为膝关节OA提供了更全面的描述和测量。
