Suppr超能文献

痔病基于症状的严重程度评分的开发与验证:索德格伦评分

Development and validation of a symptom-based severity score for haemorrhoidal disease: the Sodergren score.

作者信息

Pucher P H, Qurashi M, Howell A-M, Faiz O, Ziprin P, Darzi A, Sodergren M H

机构信息

Department of Surgery and Cancer, St Mary's Hospital, Imperial College London, London, UK.

Department of Colorectal Surgery, St Mark's Hospital, London, UK.

出版信息

Colorectal Dis. 2015 Jul;17(7):612-8. doi: 10.1111/codi.12903.

Abstract

AIM

One major obstacle in assessing the efficacy of treatment of haemorrhoids and the comparison of trials has been the lack of a standardized, validated symptom severity score. This study aimed to develop an objective, validated symptom-based score of severity for haemorrhoids that can be used to compare treatments, monitor disease and assist in surgical decisions.

METHOD

A symptom and quality-of-life questionnaire was developed from the literature in conjunction with expert surgical opinion. The questionnaire was circulated to patients with confirmed haemorrhoids. A statistical model was used to derive a weighted score of symptoms most affecting patients' quality of life. Patients who were offered operative treatment were independently judged by specialists to have more severe symptoms, with further validation of the scoring system against treatment.

RESULTS

Forty-five patients were included in final validation analysis, of whom 44 (98%) reported multiple symptoms, the most common being rectal bleeding. Patient-reported effects on quality of life were 47.5 ± 36.3 (1-100 visual analogue scale). Calculated symptom severity scores were used to compare patients receiving operative or ambulatory care, with significant difference in the scores (7.7 ± 3.9 vs 2.8 ± 3.5, P = 0.002) and a receiver operating characteristic area under the curve of 0.842.

CONCLUSION

A novel validated score for the assessment of haemorrhoidal disease adopting a standardized global score for symptom severity may have important implications in future for research, assessment and the management of this common pathology.

摘要

目的

评估痔疮治疗效果及比较相关试验的一个主要障碍是缺乏标准化、经过验证的症状严重程度评分。本研究旨在开发一种客观、经过验证的基于症状的痔疮严重程度评分,可用于比较治疗方法、监测疾病并辅助手术决策。

方法

结合文献及外科专家意见制定了一份症状与生活质量问卷。该问卷分发给确诊为痔疮的患者。使用统计模型得出对患者生活质量影响最大的症状的加权评分。接受手术治疗的患者由专家独立判断症状更严重,并通过与治疗情况对比进一步验证评分系统。

结果

45例患者纳入最终验证分析,其中44例(98%)报告有多种症状,最常见的是直肠出血。患者报告的对生活质量的影响为47.5±36.3(1 - 100视觉模拟量表)。计算得出的症状严重程度评分用于比较接受手术治疗或非手术治疗的患者,评分有显著差异(7.7±3.9对2.8±3.5,P = 0.002),曲线下面积为0.842。

结论

一种采用标准化整体症状严重程度评分的新型、经过验证的痔疮疾病评估评分可能在未来对这种常见病症的研究、评估及管理具有重要意义。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验