• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

通过抗体捕获VIDISCA-454技术鉴定一种新型人类鼻病毒C型

Identification of a novel human rhinovirus C type by antibody capture VIDISCA-454.

作者信息

Jazaeri Farsani Seyed Mohammad, Oude Munnink Bas B, Canuti Marta, Deijs Martin, Cotten Matthew, Jebbink Maarten F, Verhoeven Joost, Kellam Paul, Loens Katherine, Goossens Herman, Ieven Margareta, van der Hoek Lia

机构信息

Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center of the University of Amsterdam, Amsterdam 1105 AZ, the Netherlands.

Department of Virus Genomics, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.

出版信息

Viruses. 2015 Jan 19;7(1):239-51. doi: 10.3390/v7010239.

DOI:10.3390/v7010239
PMID:25606972
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4306836/
Abstract

Causative agents for more than 30 percent of respiratory infections remain unidentified, suggesting that unknown respiratory pathogens might be involved. In this study, antibody capture VIDISCA-454 (virus discovery cDNA-AFLP combined with Roche 454 high-throughput sequencing) resulted in the discovery of a novel type of rhinovirus C (RV-C). The virus has an RNA genome of at least 7054 nt and carries the characteristics of rhinovirus C species. The gene encoding viral protein 1, which is used for typing, has only 81% nucleotide sequence identity with the closest known RV-C type, and, therefore, the virus represents the first member of a novel type, named RV-C54.

摘要

超过30%的呼吸道感染病原体仍未明确，这表明可能存在未知的呼吸道病原体。在本研究中，抗体捕获VIDISCA-454（病毒发现cDNA-AFLP与罗氏454高通量测序相结合）发现了一种新型鼻病毒C（RV-C）。该病毒具有至少7054 nt的RNA基因组，并具有鼻病毒C种的特征。用于分型的病毒蛋白1编码基因与最接近的已知RV-C型仅有81%的核苷酸序列同一性，因此，该病毒代表了一种新型的首个成员，命名为RV-C54。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/ae75172d0a6c/viruses-07-00239-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/5f93eb73b5d0/viruses-07-00239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/97089de976fa/viruses-07-00239-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/90c1b6095cd1/viruses-07-00239-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/ae75172d0a6c/viruses-07-00239-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/5f93eb73b5d0/viruses-07-00239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/97089de976fa/viruses-07-00239-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/90c1b6095cd1/viruses-07-00239-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/091f/4306836/ae75172d0a6c/viruses-07-00239-g004.jpg

相似文献

1
Identification of a novel human rhinovirus C type by antibody capture VIDISCA-454.通过抗体捕获VIDISCA-454技术鉴定一种新型人类鼻病毒C型
Viruses. 2015 Jan 19;7(1):239-51. doi: 10.3390/v7010239.
2
Clinical severity and molecular typing of human rhinovirus C strains during a fall outbreak affecting hospitalized patients.秋季影响住院患者的疫情期间人鼻病毒C株的临床严重程度及分子分型
J Clin Virol. 2009 Aug;45(4):311-7. doi: 10.1016/j.jcv.2009.04.016. Epub 2009 May 26.
3
Phylogenetic and cluster analysis of human rhinovirus species A (HRV-A) isolated from children with acute respiratory infections in Yamagata, Japan.日本山形县儿童急性呼吸道感染分离的人鼻病毒 A 型（HRV-A）的系统发育和聚类分析。
Virus Res. 2010 Feb;147(2):265-74. doi: 10.1016/j.virusres.2009.11.011. Epub 2009 Nov 27.
4
Molecular epidemiology of human rhinovirus C in patients with acute respiratory tract infections in Osaka City, Japan.日本大阪市急性呼吸道感染患者中人鼻病毒 C 的分子流行病学研究。
Jpn J Infect Dis. 2011;64(6):488-92.
5
Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil.在巴西因急性呼吸道感染入院的儿童中检测鼻病毒C型。
J Med Virol. 2016 Jan;88(1):58-63. doi: 10.1002/jmv.24300.
6
Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: Preliminary data.鼻病毒与囊性纤维化患儿加重的相关性：初步数据。
J Med Virol. 2017 Aug;89(8):1494-1497. doi: 10.1002/jmv.24794. Epub 2017 Mar 14.
7
Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco.在摩洛哥住院儿童中，鼻病毒C与喘息相关，鼻病毒A与肺炎相关。
J Med Virol. 2017 Apr;89(4):582-588. doi: 10.1002/jmv.24684. Epub 2016 Sep 30.
8
Human Rhinoviruses in Adult Patients in a Tertiary Care Hospital in Germany: Molecular Epidemiology and Clinical Significance.德国一家三级保健医院成人患者中的人类鼻病毒：分子流行病学和临床意义。
Viruses. 2021 Oct 8;13(10):2027. doi: 10.3390/v13102027.
9
Recombination in the evolution of human rhinovirus genomes.人鼻病毒基因组进化中的重组。
Arch Virol. 2013 Jul;158(7):1497-515. doi: 10.1007/s00705-013-1634-6. Epub 2013 Feb 27.
10
[Human rhinovirus with different genotypes in children with acute respiratory tract infections in Beijing].[北京急性呼吸道感染儿童中不同基因型的人鼻病毒]
Bing Du Xue Bao. 2013 Mar;29(2):97-105.

本文引用的文献

1
Metagenomic analysis of a sample from a patient with respiratory tract infection reveals the presence of a γ-papillomavirus.对一名呼吸道感染患者的样本进行宏基因组分析，结果显示存在一种γ-乳头瘤病毒。
Front Microbiol. 2014 Jul 8;5:347. doi: 10.3389/fmicb.2014.00347. eCollection 2014.
2
Prolonged shedding of rhinovirus and re-infection in adults with respiratory tract illness.呼吸道疾病成人患者中鼻病毒持续脱落和再感染。
Eur Respir J. 2014 Jul;44(1):169-77. doi: 10.1183/09031936.00172113. Epub 2014 May 29.
3
Full genome virus detection in fecal samples using sensitive nucleic acid preparation, deep sequencing, and a novel iterative sequence classification algorithm.
使用灵敏的核酸制备、深度测序和一种新型迭代序列分类算法对粪便样本进行全基因组病毒检测。
PLoS One. 2014 Apr 2;9(4):e93269. doi: 10.1371/journal.pone.0093269. eCollection 2014.
4
Population structure and evolution of Rhinoviruses.鼻病毒的种群结构与进化。
PLoS One. 2014 Feb 19;9(2):e88981. doi: 10.1371/journal.pone.0088981. eCollection 2014.
5
Viruses associated with acute respiratory infections and influenza-like illness among outpatients from the Influenza Incidence Surveillance Project, 2010-2011.2010-2011 年流感监测项目中门诊急性呼吸道感染和流感样疾病的相关病毒。
J Infect Dis. 2014 Jun 1;209(11):1715-25. doi: 10.1093/infdis/jit806. Epub 2013 Dec 12.
6
Autologous antibody capture to enrich immunogenic viruses for viral discovery.利用自身抗体捕获技术富集免疫原性病毒，用于病毒发现。
PLoS One. 2013 Nov 4;8(11):e78454. doi: 10.1371/journal.pone.0078454. eCollection 2013.
7
Identification of a new genotype of Torque Teno Mini virus.鉴定出一种新型的扭结瘤病毒基因型。
Virol J. 2013 Oct 30;10:323. doi: 10.1186/1743-422X-10-323.
8
MEGA6: Molecular Evolutionary Genetics Analysis version 6.0.MEGA6：分子进化遗传学分析版本 6.0。
Mol Biol Evol. 2013 Dec;30(12):2725-9. doi: 10.1093/molbev/mst197. Epub 2013 Oct 16.
9
Growth and characterization of different human rhinovirus C types in three-dimensional human airway epithelia reconstituted in vitro.不同人呼吸道肠道病毒 C 型在体外三维重建的人呼吸道上皮细胞中的生长和特征。
Virology. 2013 Nov;446(1-2):1-8. doi: 10.1016/j.virol.2013.06.031. Epub 2013 Aug 7.
10
Identification of a new cyclovirus in cerebrospinal fluid of patients with acute central nervous system infections.鉴定急性中枢神经系统感染患者脑脊液中的一种新型环状病毒。
mBio. 2013 Jun 18;4(3):e00231-13. doi: 10.1128/mBio.00231-13.