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多光谱数字皮肤病变分析在儿童痣评估中的应用。

Use of multispectral digital skin lesion analysis for evaluation of nevi in children.

作者信息

Dorizas Andrew S, Nassar Amer H, Goldberg David J

出版信息

J Drugs Dermatol. 2014 Oct;13(10):1269-73.

Abstract

OBJECTIVE

We determine if the use of Multispectral Digital Skin Lesion Analysis for the evaluation of nevi in children and possible detection of malignancies.

EVIDENCE REVIEW

Evidence gathered from a pivotal study involving 1,383 patients with 1,831-pigmented lesions. The isolated use of the pediatric population within this study was used to determine the specificity and sensitivity of such a device with comparison to a dermatologists evaluation.

FINDINGS

For all lesions from the assessed pediatric population the biopsy ratio was equivalent for the Multispectral Digital Skin Lesion Analysis device as for the dermatologists when performing as independent reviewers. Furthermore analyzed data suggests that dermatologists who incorporate the Multispectral Digital Skin Lesion Analysis device perform better than they would independently or if they were to follow the device blindly without incorporating their own judgment.

CONCLUSION AND RELEVANCE

An approach that integrates automated imaging technology like the Multispectral Digital Skin Lesion Analysis device, along with another diagnostic aid, with the end result being cost-effective, easy to use by even non-experts and comforting for the pediatric patient is likely to compete to be the new gold standard in successful early diagnosis and management of melanoma.

摘要

目的

我们确定使用多光谱数字皮肤病变分析来评估儿童痣以及可能检测恶性肿瘤的情况。

证据综述

从一项涉及1383名患者和1831个色素沉着病变的关键研究中收集证据。本研究中仅使用儿科人群来确定该设备与皮肤科医生评估相比的特异性和敏感性。

研究结果

对于评估的儿科人群中的所有病变,当作为独立评估者时,多光谱数字皮肤病变分析设备的活检率与皮肤科医生的活检率相当。此外,分析数据表明,结合使用多光谱数字皮肤病变分析设备的皮肤科医生比他们独立工作时或盲目遵循该设备而不结合自己的判断时表现更好。

结论与意义

一种将多光谱数字皮肤病变分析设备等自动成像技术与另一种诊断辅助工具相结合的方法,最终具有成本效益、即使非专家也易于使用且能让儿科患者感到安心,很可能会成为成功早期诊断和管理黑色素瘤的新金标准。

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