Divchev Dimitar, Najjar Tarek, Tillwich Falko, Rehders Tim, Palisch Holger, Nienaber Christoph A
Department of Cardiology, Heart Center, University Hospital Rostock, D-18057 Rostock, Germany.
Expert Rev Cardiovasc Ther. 2015 Mar;13(3):325-31. doi: 10.1586/14779072.2015.1004313. Epub 2015 Jan 21.
Acute aortic disease ranks as the 19th leading cause of death with steadily increasing incidence. The prevalence of aneurysms varies depending on the localization along the aorta with a mortality of aortic rupture of around 80%. Traditionally, aortic disease affects men more frequently than women, however, with a varying gender ratio. Nevertheless, in the setting of acute aortic dissection, the International Registry of Acute Aortic Dissections identified significant gender-related differences in the management of both sexes with acute aortic conditions. Current data suggest that women are at an increased risk of both dying from aortic dissection and having aorta-related complications than men. This review aims to report on current evidence of gender impact on natural history, treatment and outcomes in patients with acute aortic dissection.
急性主动脉疾病是第19大致死原因，发病率呈稳步上升趋势。动脉瘤的患病率因主动脉的部位不同而有所差异，主动脉破裂的死亡率约为80%。传统上，主动脉疾病在男性中的发病率高于女性，不过性别比例有所不同。然而，在急性主动脉夹层的情况下，国际急性主动脉夹层注册研究发现，在急性主动脉疾病的治疗方面，两性存在显著的性别差异。目前的数据表明，与男性相比，女性死于主动脉夹层和发生主动脉相关并发症的风险更高。本综述旨在报告关于性别对急性主动脉夹层患者的自然病程、治疗及预后影响的现有证据。
