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腹腔镜左侧入路行胰上淋巴结清扫术治疗进展期胃癌

Laparoscopic Suprapancreatic Lymph Node Dissection for Advanced Gastric Cancer Using a Left-Sided Approach.

作者信息

Huang Chang-Ming, Chen Qi-Yue, Lin Jian-Xian, Zheng Chao-Hui, Li Ping, Xie Jian-Wei, Wang Jia-Bin, Lu Jun, Yang Xin-Tao

机构信息

Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China,

出版信息

Ann Surg Oncol. 2015 Jul;22(7):2351. doi: 10.1245/s10434-014-4309-y. Epub 2015 Jan 22.

Abstract

BACKGROUND

We developed a novel procedure for laparoscopic suprapancreatic lymph node (LN) dissection, which is compulsory and quite difficult for patients with advanced gastric cancer.1 (-) 3 METHODS: We dissected suprapancreatic LNs from the left to the right side. The No. 11p LNs were dissected first, followed by the No. 9, 7, and 8a LNs. Dissection of the No. 5 and 12a LNs was completed last. The above procedure was performed on 814 consecutive patients with stage cT2-3 disease.

RESULTS

Mean operation time was 186.9 ± 56.4 min (range 80-480 min), mean blood loss was 76.6 ± 106.8 ml (range 3-500 ml), and mean times to first flatus, fluid diet, and soft diet were 3.7 ± 1.2 days (range 1-9 days), 5.2 ± 1.7 days (range 2-14 days), and 8.3 ± 2.2 days (range 5-20 days), respectively. A mean 34.5 ± 12.9 LNs (range 22-103) were retrieved, including a mean 12.4 ± 5.7 (range 0-35) suprapancreatic area LNs. Overall postoperative morbidity rate was 14.7 % (120/814), including three cases of pancreatic fistula. All of these postoperative complications were successfully treated by conservative methods. At a median follow-up of 27 months (range 1-63), cumulative 3-year overall survival was 59.2 %.

CONCLUSION

Laparoscopic suprapancreatic LN dissection using a left-sided approach could be safely achieved and is more convenient for advanced gastric cancer.

摘要

背景

我们研发了一种新型的腹腔镜胰上淋巴结(LN)清扫术,对于进展期胃癌患者而言,该手术是必要的且颇具难度。1(-)3 方法:我们从左侧向右侧清扫胰上淋巴结。首先清扫11p组淋巴结,接着清扫9、7和8a组淋巴结。最后完成5和12a组淋巴结的清扫。上述手术步骤应用于814例连续的cT2 - 3期疾病患者。

结果

平均手术时间为186.9±56.4分钟(范围80 - 480分钟),平均失血量为76.6±106.8毫升(范围3 - 500毫升),首次排气、流食和软食的平均时间分别为3.7±1.2天(范围1 - 9天)、5.2±1.7天(范围2 - 14天)和8.3±2.2天(范围5 - 20天)。平均获取34.5±12.9枚淋巴结(范围22 - 103枚),其中胰上区域平均获取12.4±5.7枚(范围0 - 35枚)。术后总体并发症发生率为14.7%(120/814),包括3例胰瘘。所有这些术后并发症均通过保守方法成功治疗。中位随访27个月(范围1 - 63个月)时,3年累积总生存率为59.2%。

结论

采用左侧入路的腹腔镜胰上淋巴结清扫术可安全实施,且对进展期胃癌更为便利。

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