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《波士顿人工角膜眼内炎:病例系列及文献综述》勘误

Erratum to: Endophthalmitis in Boston keratoprosthesis: case series and review of literature.

作者信息

Chhablani Jay, Panchal Bhavik, Das Taraparasad, Pathengay Avinash, Motukupally Swapna R, Pappuru Rajeev Reddy, Basu Sayan, Sangwan Virender

机构信息

Srimati Kanuri Santhamma Vitreo-Retina Service, L.V. Prasad Eye Institute, L. V. Prasad Marg, Banjara Hills, Hyderabad, India.

GMR Valalakshmi Campus, L V Prasad Eye Institute, Vishakhapatnam, India.

出版信息

Int Ophthalmol. 2015 Feb;35(1):149-54. doi: 10.1007/s10792-014-0033-7.

DOI:10.1007/s10792-014-0033-7
PMID:25609502
Abstract

To report the clinical and microbiological characteristics of infectious endophthalmitis after Boston type I keratoprosthesis (B-K-Pro) implantation. Retrospective analysis of 45 eyes that received a B-K-Pro type 1 between 2009 and 2012 was performed. Five eyes with a diagnosis of exogenous endophthalmitis after B-K-pro type 1 were identified and information about demographic data, indication for K-Pro, post-operative bandage contact lens use, post-operative prophylactic antibiotic use, timing and clinical presentation of endophthalmitis, gram stain and culture results of intraocular fluid and preoperative and post-operative visual acuity were collected. The incidence of endophthalmitis was 11.1 % (5 of 45 eyes) and average time to develop endophthalmitis was 5.62 months (range 2 days to 8 months). Mean patient age was 31.4 years (5 to 65 years). The surgical indications included corneal injury due to chemical burns (n = 2), multiple failed grafts secondary to microbial keratitis (n = 2) and congenital glaucoma with congenital herpetic keratitis (n = 1). Post-Boston K-Pro, the visual acuity ranged from light perception (LP) to 20/50. K-pro was explanted in 4 patients. There was bacterial and fungal growth in two patients each and one vitreous did not grow anything. All the eyes were phthisical at last visit. Infectious endophthalmitis after K-Pro implantation in our study had a higher incidence, early onset and extremely poor visual outcome compared with post-cataract surgery endophthalmitis, as reported in literature. Not only bacterial but also fungal infections are an important etiology for infectious endophthalmitis in these cases.

摘要

报告波士顿I型人工角膜(B-K-Pro)植入术后感染性眼内炎的临床和微生物学特征。对2009年至2012年间接受1型B-K-Pro的45只眼进行回顾性分析。确定了5只诊断为1型B-K-Pro术后外源性眼内炎的眼睛,并收集了有关人口统计学数据、人工角膜植入指征、术后绷带接触镜使用情况、术后预防性抗生素使用情况、眼内炎的发生时间和临床表现、眼内液的革兰氏染色和培养结果以及术前和术后视力的信息。眼内炎的发生率为11.1%(45只眼中的5只),发生眼内炎的平均时间为5.62个月(范围为2天至8个月)。患者平均年龄为31.4岁(5至65岁)。手术指征包括化学烧伤导致的角膜损伤(n = 2)、微生物性角膜炎继发的多次移植失败(n = 2)以及先天性青光眼合并先天性疱疹性角膜炎(n = 1)。植入波士顿K-Pro后,视力范围从光感(LP)到20/50。4例患者取出了人工角膜。2例患者的眼内液有细菌和真菌生长,1例玻璃体未培养出任何东西。最后一次随访时所有眼睛均萎缩。与文献报道的白内障手术后眼内炎相比,我们研究中K-Pro植入术后感染性眼内炎的发生率更高、发病更早且视力预后极差。在这些病例中,不仅细菌感染,真菌感染也是感染性眼内炎的重要病因。

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本文引用的文献

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Infectious keratitis after Boston type 1 keratoprosthesis implantation.波士顿 1 型角膜假体植入术后感染性角膜炎。
Cornea. 2012 Oct;31(10):1128-34. doi: 10.1097/ICO.0b013e318245c02a.
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Case control analyses of acute endophthalmitis after cataract surgery in South India associated with technique, patient care, and socioeconomic status.印度南部白内障手术后急性眼内炎与手术技术、患者护理及社会经济地位的病例对照分析。
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Infectious endophthalmitis in adult eyes receiving Boston type I keratoprosthesis.
成人 Boston Ⅰ型角膜移植术后眼感染性眼内炎。
Ophthalmology. 2012 Apr;119(4):674-81. doi: 10.1016/j.ophtha.2011.10.009. Epub 2012 Jan 23.
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Characteristics of endophthalmitis in patients with the Boston keratoprosthesis.波士顿人工角膜患者眼内炎的特征
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Fungal colonization and infection in Boston keratoprosthesis.波士顿人工角膜中的真菌定植与感染
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