Patel Kiran Haresh Kumar, Lambiase Pier D
Department of Cardiology, The Heart Hospital, University College London, London W1G 8PH, UK.
Cardiovasc Diagn Ther. 2014 Dec;4(6):449-59. doi: 10.3978/j.issn.2223-3652.2014.12.02.
The subcutaneous implantable cardioverter-defibrillator (S-ICD) represents an exciting development in ICD technology. It has relative advantages over traditional transvenous systems, particularly for young patients in whom the lifetime risk of device-related complications may be deemed to be unacceptably high. While data relating to device longevity and long term safety profile is yet to be accrued, several recent studies have demonstrated good clinical efficacy comparable to transvenous ICDs. Indeed, new techniques have also been developed to simplify the S-ICD implantation procedure and attempts have been made to address challenges pertaining to T-wave oversensing to reduce the delivery of inappropriate shocks. The impact of inappropriate shocks and lack of anti-tachycardia pacing (ATP) function are not only contentious matters, but also have important implications for patients in whom the S-ICD would be suitable. It is envisaged that subsequent models of this device will be less cumbersome, with the possibility that an entirely leadless pacemaker-defibrillator will one day be possible. Although the S-ICD may not completely replace transvenous devices in its current form, evidence suggests that it is a viable alternative particularly in preventing sudden cardiac death in non-pacing dependent patients.
皮下植入式心律转复除颤器(S-ICD)是ICD技术一项令人振奋的进展。与传统经静脉系统相比,它具有相对优势,对于年轻患者而言,与设备相关并发症的终身风险可能被认为高得不可接受。虽然有关设备寿命和长期安全性的数据尚未积累,但最近的几项研究已证明其临床疗效良好,与经静脉ICD相当。事实上,还开发了新技术来简化S-ICD植入程序,并已尝试应对与T波过度感知相关的挑战,以减少不适当电击的发放。不适当电击的影响以及缺乏抗心动过速起搏(ATP)功能不仅是有争议的问题,而且对适合使用S-ICD的患者也有重要影响。可以设想,该设备的后续型号将不那么笨重,并且有可能有朝一日实现完全无导线的起搏器-除颤器。尽管S-ICD目前的形式可能无法完全取代经静脉设备,但有证据表明它是一种可行的替代方案,特别是在预防非起搏依赖患者的心源性猝死方面。