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将慢性肌肉骨骼疾病患者分类为心理社会亚组能否预测功能恢复计划后的差异治疗反应和1年结局?

Does Classification of Chronic Musculoskeletal Disorder Patients Into Psychosocial Subgroups Predict Differential Treatment Responsiveness and 1-Year Outcomes After a Functional Restoration Program?

作者信息

Asih Sali, Mayer Tom G, Williams Mark, Choi Yun Hee, Gatchel Robert J

机构信息

*PRIDE Research Foundation †Department of Orthopedic Surgery, The University of Texas Southwestern Medical Center at Dallas, Dallas ‡Department of Psychology, College of Science, The University of Texas at Arlington, Arlington, TX.

出版信息

Clin J Pain. 2015 Dec;31(12):1036-45. doi: 10.1097/AJP.0000000000000216.

Abstract

OBJECTIVES

The objectives of this study: (1) to assess whether Multidimensional Pain Inventory (MPI) profiles predicted differential responses to a functional restoration program (FRP) in chronic disabling occupational musculoskeletal disorder (CDOMD) patients; (2) to examine whether coping style improves following FRP; and (3) to determine whether discharge MPI profiles predict discharge psychosocial and 1-year socioeconomic outcomes.

METHODS

Consecutive CDOMD patients (N=716) were classified into Adaptive Coper (AC, n=209), Interpersonally Distressed (ID, n=154), Dysfunctional (DYS, n=310), and Anomalous (n=43) using the MPI, and reclassified at discharge. Profiles were compared on psychosocial measures and 1-year socioeconomic outcomes. An intent-to-treat sample analyzed the effect of drop-outs on treatment responsiveness.

RESULTS

The MPI classification significantly predicted program completion (P=0.001), although the intent-to-treat analyses found no significant effects of drop-out on treatment responsiveness. There was a significant increase in the number of patients who became AC or Anomalous at FRP discharge and a decrease in those who were ID or DYS. Patients who changed or remained as DYS at FRP discharge reported the highest levels of pain, disability, and depression. No significant interaction effect was found between MPI group and time for pain intensity or disability. All groups improved on psychosocial measures at discharge. DYS patients had decreased work retention and a greater health care utilization at 1 year.

CONCLUSIONS

An FRP was clinically effective for CDOMD patients regardless of initial MPI profiles. The FRP modified profiles, with patients changing from negative to positive profiles. Discharge DYS were more likely to have poor 1-year outcomes. Those classified as Anomalous had a good prognosis for functional recovery similar to ACs.

摘要

目的

本研究的目的包括:(1)评估多维疼痛量表(MPI)剖面图是否能预测慢性致残性职业性肌肉骨骼疾病(CDOMD)患者对功能恢复计划(FRP)的不同反应;(2)检查FRP实施后应对方式是否有所改善;(3)确定出院时的MPI剖面图是否能预测出院时的心理社会状况和1年的社会经济结果。

方法

连续纳入的CDOMD患者(N = 716)使用MPI分为适应性应对者(AC,n = 209)、人际困扰者(ID,n = 154)、功能失调者(DYS,n = 310)和异常者(n = 43),并在出院时重新分类。比较各剖面图在心理社会指标和1年社会经济结果方面的差异。意向性治疗样本分析了失访对治疗反应性的影响。

结果

MPI分类显著预测了项目完成情况(P = 0.001),尽管意向性治疗分析发现失访对治疗反应性没有显著影响。在FRP出院时成为AC或异常者的患者数量显著增加,而ID或DYS者数量减少。在FRP出院时仍为DYS或转变为DYS的患者报告的疼痛、残疾和抑郁水平最高。MPI组与时间之间在疼痛强度或残疾方面未发现显著的交互作用。所有组在出院时心理社会指标均有改善。DYS患者在1年时工作保留率降低,医疗保健利用率更高。

结论

无论初始MPI剖面图如何,FRP对CDOMD患者在临床上都是有效的。FRP改变了剖面图,患者从负面剖面图转变为正面剖面图。出院时为DYS的患者1年结局较差的可能性更大。分类为异常者与AC者在功能恢复方面预后良好。

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