索非布韦在治疗丙型肝炎感染中起什么作用？

What is the role of sofosbuvir in treating hepatitis C infection?

作者信息

Carey Lawrence

机构信息

Lawrence Carey is a clinical associate professor in the Temple University School of Pharmacy and a lecturer in pharmacotherapeutics and former program director of the Philadelphia University PA program, both in Philadelphia, Pa. The author has disclosed no potential conflicts of interest, financial or otherwise.

出版信息

JAAPA. 2015 Feb;28(2):16-9. doi: 10.1097/01.JAA.0000459818.09661.c0.

DOI:10.1097/01.JAA.0000459818.09661.c0

PMID:25621961

Abstract

Sofosbuvir, a nucleotide polymerase inhibitor, was approved in 2013 for treating hepatitis C infection in adults. This article reviews the use of sofosbuvir in combination with ribavirin with or without pegylated interferon.

摘要

索磷布韦是一种核苷酸聚合酶抑制剂，于2013年被批准用于治疗成人丙型肝炎感染。本文综述了索磷布韦与利巴韦林联合使用（有或没有聚乙二醇化干扰素）的情况。