我发现了同种反应性 T 细胞。
I spy alloreactive T cells.
机构信息
Department of Medicine, University of Chicago, Chicago, IL 60637, USA.
出版信息
Sci Transl Med. 2015 Jan 28;7(272):272fs3. doi: 10.1126/scitranslmed.aaa5083.
PMID:25632032
Abstract
High-throughput sequencing of the T cell receptor Vβ CDR3 region allowed longitudinal tracking of alloreactive T cells in kidney transplant patients, revealing clonal deletion as a mechanism of transplantation tolerance (Morris et al., this issue).
摘要
高通量测序 T 细胞受体 Vβ CDR3 区可实现对肾移植患者同种反应性 T 细胞的纵向跟踪，揭示克隆删除是移植耐受的机制（Morris 等人，本期）。
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