Suppr超能文献

肾脏钳夹、灌注、再植入:肾移植血管并发症后挽救移植物的一项有用技术。

Kidney clamp, perfuse, re-implant: a useful technique for graft salvage after vascular complications during kidney transplantation.

作者信息

Mekeel Kristin L, Halldorson Jeffery B, Berumen Jennifer A, Hemming Alan W

机构信息

Division of Transplantation and Hepatobiliary Surgery, University of California San Diego, San Diego, CA, USA.

出版信息

Clin Transplant. 2015 Apr;29(4):373-8. doi: 10.1111/ctr.12526. Epub 2015 Mar 9.

Abstract

Although intra-operative vascular complications during renal transplantation are rare, injuries associated with prolonged ischemia may lead to graft threatening early and late complications. This series describes a novel technique for intra-operative repair of vascular complications in five patients over a three-yr period. The method consists of rapid graft nephrectomy and re-preservation of the graft with cold University of Wisconsin solution, which allows for controlled/precise back table repair of the vascular injury without incurring prolonged warm ischemia time. In three cases, the donor renal vein (2) and donor renal artery (1) were damaged and required back table reconstruction. In two cases, the recipient iliac artery needed reconstruction. Three of the five cases used deceased donor iliac vessels from another donor for reconstruction. Two patients required postoperative dialysis for delayed graft function for three to nine d (average six d) and two patients had slow graft function. All grafts were functioning at 17 months (mean) after transplant, with a median serum of 1.61 mg/dL (0.74-3.69). This series demonstrates the effectiveness of kidney clamp, perfuse, resuscitate as an effective intra-operative technique to salvage grafts after vascular injury. Although the grafts may suffer from delayed or slow graft function, excellent long-term function is attainable.

摘要

尽管肾移植术中血管并发症很少见,但与长时间缺血相关的损伤可能导致移植肾出现早期和晚期的严重并发症。本系列描述了一种在三年期间对五例患者进行术中血管并发症修复的新技术。该方法包括快速切除移植肾并用冷的威斯康星大学溶液重新保存移植肾,这使得在不延长热缺血时间的情况下,能够在体外对血管损伤进行可控/精确修复。三例中,供体肾静脉(2例)和供体肾动脉(1例)受损,需要在体外进行重建。两例中,受体髂动脉需要重建。五例中有三例使用了来自另一个供体的尸体供体髂血管进行重建。两名患者因移植肾功能延迟需术后透析三至九天(平均六天),两名患者移植肾功能恢复缓慢。所有移植肾在移植后17个月(平均)时均功能良好,血清肌酐中位数为1.61mg/dL(0.74 - 3.69)。本系列证明了肾钳夹、灌注、复苏作为一种有效的术中技术,可在血管损伤后挽救移植肾。尽管移植肾可能出现功能延迟或恢复缓慢,但可实现良好的长期功能。

相似文献

3
Independent risk factors for early urologic complications after kidney transplantation.
Clin Transplant. 2015 May;29(5):403-8. doi: 10.1111/ctr.12530. Epub 2015 Mar 6.
4
[Treatment techniques of harvesting injury of donor renal blood vessels].
Zhonghua Wai Ke Za Zhi. 2004 May 22;42(10):607-10.
5
Peri-operative hyperglycemia is associated with delayed graft function in deceased donor renal transplantation.
Clin Transplant. 2013 Jul-Aug;27(4):E424-30. doi: 10.1111/ctr.12174. Epub 2013 Jun 30.
6
Vascular challenges in renal transplantation.
Ann Transplant. 2014 Sep 19;19:464-71. doi: 10.12659/AOT.890893.

引用本文的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验