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使用心肺运动试验预测腹主动脉瘤修复术后的器官特异性并发症。

Prediction of organ-specific complications following abdominal aortic aneurysm repair using cardiopulmonary exercise testing.

机构信息

Academic Vascular Surgical Unit, University of Hull & Hull York Medical School, Hull Royal Infirmary, Hull, UK.

出版信息

Anaesthesia. 2015 Jun;70(6):679-85. doi: 10.1111/anae.12986. Epub 2015 Feb 6.

Abstract

This study aimed at assessing whether measures of aerobic fitness can predict postoperative cardiac and pulmonary complications, 30-day mortality and length of hospital stay following elective abdominal aortic aneurysm repair. We prospectively collected cardiopulmonary exercise testing data over two years for 130 patients. Upon multivariate analysis, a decreased anaerobic threshold (OR (95% CI) 0.55 (0.37-0.84); p = 0.005) and open repair (OR (95% CI) 6.99 (1.56-31.48); p = 0.011) were associated with cardiac complications. Similarly, an increased ventilatory equivalent for carbon dioxide (OR (95% CI) 1.18 (1.05-1.33); p = 0.005) and open repair (OR (95% CI) 14.29 (3.24-62.90); p < 0.001) were associated with pulmonary complications. Patients who had an endovascular repair had shorter hospital and critical care lengths of stay (p < 0.001). Measures of fitness were not associated with 30-day mortality or length of hospital stay. Cardiopulmonary exercise testing variables, therefore, seem to predict different postoperative complications following abdominal aortic aneurysm repair, which adds value to their routine use in risk stratification and optimisation of peri-operative care.

摘要

本研究旨在评估有氧适能测量是否可以预测择期腹主动脉瘤修复术后的心脏和肺部并发症、30 天死亡率和住院时间。我们在两年内前瞻性地收集了 130 例患者的心肺运动测试数据。在多变量分析中,无氧阈值降低(OR(95%CI)0.55(0.37-0.84);p=0.005)和开放修复(OR(95%CI)6.99(1.56-31.48);p=0.011)与心脏并发症相关。同样,二氧化碳通气当量增加(OR(95%CI)1.18(1.05-1.33);p=0.005)和开放修复(OR(95%CI)14.29(3.24-62.90);p<0.001)与肺部并发症相关。接受血管内修复的患者住院和重症监护时间更短(p<0.001)。适能测量值与 30 天死亡率或住院时间无关。因此,心肺运动测试变量似乎可以预测腹主动脉瘤修复术后的不同术后并发症,这为其在风险分层和优化围手术期护理中的常规应用增加了价值。

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