Lezanski-Gujda Amanda, Bingham Jonathan L, Logemann Nicholas F
Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Indian Dermatol Online J. 2015 Jan-Feb;6(1):1-3. doi: 10.4103/2229-5178.148906.
Hyperhidrosis-related to prosthesis use in patients who have suffered a traumatic limb amputation presents itself as a barrier to comfort, prosthesis use and overall quality of life. This review intends to encourage dermatologists to consider the use of botulinum toxin A or B for the treatment of hyperhidrosis in the residual limb and may serve as a stimulus for a modern, in-depth, and more comprehensive study. A review of the literature was conducted using the PubMed database, focusing on hyperhidrosis treatment after traumatic limb amputation. Articles discussing hyperhidrosis treatment for amputations secondary to chronic medical conditions were excluded. Seven case studies published over the last 12 years have demonstrated positive outcomes of this treatment strategy. Overall, there is little data examining this topic and current publications focus primarily on small case series. A larger, double-blind, placebo-controlled study would likely benefit veterans, service members, and civilians.
在遭受外伤性肢体截肢的患者中，与假肢使用相关的多汗症是影响舒适度、假肢使用及整体生活质量的一个障碍。本综述旨在促使皮肤科医生考虑使用A型或B型肉毒杆菌毒素治疗残肢多汗症，并可能推动开展一项现代、深入且更全面的研究。我们使用PubMed数据库对文献进行了综述，重点关注外伤性肢体截肢后的多汗症治疗。排除了讨论因慢性疾病导致截肢的多汗症治疗的文章。过去12年发表的7个病例研究证明了这种治疗策略的积极效果。总体而言，研究该主题的数据很少，当前的出版物主要集中在小病例系列。一项更大规模的双盲、安慰剂对照研究可能会使退伍军人、现役军人和平民受益。
