Wang Yufei, Joannic David, Delassus Patrick, Lalande Alain, Juillion Patrick, Fontaine Jean-François
Laboratoire d'électronique, informatique et image, UMR CNRS 6306, Université de Bourgogne site d'Auxerre, route des plaines de l'Yonne, 89000 Auxerre, France.
Laboratoire d'électronique, informatique et image, UMR CNRS 6306, Université de Bourgogne site d'Auxerre, route des plaines de l'Yonne, 89000 Auxerre, France; IUT Dijon-Auxerre, route des plaine de l'Yonne, 89000 Auxerre, France.
J Biomech. 2015 Apr 13;48(6):1158-64. doi: 10.1016/j.jbiomech.2015.01.017. Epub 2015 Jan 21.
The prediction of the risk of rupture of abdominal aortic aneurysm (AAA) is a complex problem. Currently the criteria to predict rupture of abdominal aortic aneurysms are aneurysm diameter and growth rates. It is generally believed that study of the wall strain distribution could be helpful to find a better decision criterion for surgery of aortic aneurysms before their rupture. The wall strain distribution depends on many biological and biomechanical factors such as elastic properties of the aorta, turbulent blood flow, anatomy of the aorta, presence of thrombus or not and so on. Recently, numerical simulations to estimate rupture-potential have received many attentions. However, none of the medical imaging tools for screening and monitoring of AAAs were studied in terms of mechanical behavior and experimentally to demonstrate their capability to measure relevant variables. The aim of this study was to develop a metrological approach for deployment testing of the ability of techniques for measuring local in-vitro deformations based on comparison of stereovision and MRI. In this paper, we present the implementation approach and results of the study based on cylindrical phantoms with or without AAA representing, respectively, healthy and unhealthy artery. Through this study, an experimental device was developed for the behavior study of AAA during a cardiac cycle. The results show that the stereovision techniques used in laboratory is well suited and is qualitatively and quantitatively equivalent with MRI measurements.
腹主动脉瘤(AAA)破裂风险的预测是一个复杂的问题。目前,预测腹主动脉瘤破裂的标准是动脉瘤直径和生长速率。一般认为,研究血管壁应变分布有助于在主动脉瘤破裂前找到更好的手术决策标准。血管壁应变分布取决于许多生物学和生物力学因素,如主动脉的弹性特性、湍流血液流动、主动脉解剖结构、是否存在血栓等。最近,用于估计破裂可能性的数值模拟受到了广泛关注。然而,尚未从力学行为方面对用于腹主动脉瘤筛查和监测的医学成像工具进行研究,也未通过实验证明其测量相关变量的能力。本研究的目的是基于立体视觉和磁共振成像(MRI)的比较,开发一种用于测量局部体外变形技术的计量学方法,以进行部署测试。在本文中,我们展示了基于分别代表健康和不健康动脉的有或没有AAA的圆柱形模型的研究实施方法和结果。通过这项研究,开发了一种用于研究心动周期中AAA行为的实验装置。结果表明,实验室中使用的立体视觉技术非常适用,在定性和定量方面与MRI测量相当。