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心脏骤停后神经功能预后的当前实践调查。

Survey on current practices for neurological prognostication after cardiac arrest.

作者信息

Friberg Hans, Cronberg Tobias, Dünser Martin W, Duranteau Jacques, Horn Janneke, Oddo Mauro

机构信息

Skåne University Hospital, Department of Anaesthesiology and Intensive Care, Lund University, Sweden.

Skåne University Hospital, Department of Neurology, Lund University, Sweden.

出版信息

Resuscitation. 2015 May;90:158-62. doi: 10.1016/j.resuscitation.2015.01.018. Epub 2015 Feb 9.

Abstract

PURPOSE

To investigate current practices and timing of neurological prognostication in comatose cardiac arrest patients.

METHODS

An anonymous questionnaire was distributed to the 8000 members of the European Society of Intensive Care Medicine during September and October 2012. The survey had 27 questions divided into three categories: background data, clinical data, decision-making and consequences.

RESULTS

A total of 1025 respondents (13%) answered the survey with complete forms in more than 90%. Twenty per cent of respondents practiced outside of Europe. Overall, 22% answered that they had national recommendations, with the highest percentage in the Netherlands (>80%). Eighty-nine per cent used induced hypothermia (32-34 °C) for comatose cardiac arrest patients, while 11% did not. Twenty per cent had separate prognostication protocols for hypothermia patients. Seventy-nine per cent recognized that neurological examination alone is not enough to predict outcome and a similar number (76%) used additional methods. Intermittent electroencephalography (EEG), brain computed tomography (CT) scan and evoked potentials (EP) were considered most useful. Poor prognosis was defined as cerebral performance category (CPC) 3-5 (58%) or CPC 4-5 (39%) or other (3%). When prognosis was considered poor, 73% would actively withdraw intensive care while 20% would not and 7% were uncertain.

CONCLUSION

National recommendations for neurological prognostication after cardiac arrest are uncommon and only one physician out of five uses a separate protocol for hypothermia treated patients. A neurological examination alone was considered insufficient to predict outcome in comatose patients and most respondents advocated a multimodal approach: EEG, brain CT and EP were considered most useful. Uncertainty regarding neurological prognostication and decisions on level of care was substantial.

摘要

目的

探讨昏迷心脏骤停患者神经预后评估的当前实践及时机。

方法

2012年9月至10月,向欧洲重症监护医学学会的8000名成员发放了一份匿名问卷。该调查有27个问题,分为三类:背景数据、临床数据、决策制定及后果。

结果

共有1025名受访者(13%)以超过90%的完整表格回答了调查。20%的受访者在欧洲以外地区执业。总体而言,22%的受访者表示他们有国家推荐意见,荷兰的比例最高(>80%)。89%的受访者对昏迷心脏骤停患者采用诱导低温(32 - 34°C),而11%未采用。20%的受访者有针对低温治疗患者的单独预后评估方案。79%的受访者认识到仅靠神经检查不足以预测预后,类似比例(76%)使用了其他方法。间歇性脑电图(EEG)、脑部计算机断层扫描(CT)和诱发电位(EP)被认为最有用。预后不良被定义为脑功能分类(CPC)3 - 5(58%)或CPC 4 - 5(39%)或其他(3%)。当认为预后不良时,73%的人会积极撤销重症监护,20%的人不会,7%的人不确定。

结论

心脏骤停后神经预后评估的国家推荐意见并不常见,每五名医生中只有一名对低温治疗患者使用单独的方案。仅靠神经检查被认为不足以预测昏迷患者的预后,大多数受访者主张采用多模式方法:EEG、脑部CT和EP被认为最有用。神经预后评估及护理水平决策方面的不确定性很大。

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