Noureldin Yasser A, Elkoushy Mohamed A, Andonian Sero
Division of Urology, McGill University Health Centre, 687 Pine Ave. West, Suite S6.92, Montreal, QC, H3A 1A1, Canada.
Department of Urology, Benha University Hospital, Benha University, Benha, Egypt.
World J Urol. 2015 Nov;33(11):1821-5. doi: 10.1007/s00345-015-1508-5. Epub 2015 Feb 13.
The aim of the present study was to compare the accuracy of the Guy's and S.T.O.N.E. scoring systems in predicting percutaneous nephrolithotomy (PCNL) outcomes.
After obtaining ethics approval, medical records of patients undergoing PCNL between 2009 and 2013 at a tertiary stone center were retrospectively reviewed. Guy's and S.T.O.N.E. scoring systems were calculated. Regression analysis and ROC curves were performed.
A total of 185 PCNLs were reviewed. The overall stone-free rate was 71.9 % with a complication rate of 16.2 %. When compared to patients with residual fragments, stone-free patients had significantly lower Guy's grade (2.7 vs. 2; p < 0.001) and S.T.O.N.E. score (8.3 vs. 7.4; p = 0.004). Logistic regression analysis showed that both Guy's and S.T.O.N.E. systems were significantly associated with stone-free status, OR 0.4 (p < 0.001), and OR 0.7 (p = 0.001), respectively. Furthermore, both scoring systems were significantly associated with the estimated blood loss (p = 0.01 and p = 0.005). There was good correlation between both scoring systems and operative time (r = 0.3, p < 0.001 and r = 0.4, p < 0.001) and length of hospital stay (r = 0.2, p = 0.001 and r = 0.3, p < 0.001). However, there were no significant associations between both scoring systems and complications (p = 0.7 and p = 0.6). There was no significant difference in the areas under the curves for the Guy's and S.T.O.N.E. scoring systems (0.74 [95 % CI 0.66-0.82] vs. 0.63 [95 % CI 0.54-0.72]; p = 0.06).
Both Guy's and S.T.O.N.E scoring systems have comparable accuracies in predicting post-PCNL stone-free status. Other factors not included in either scoring system may need to be incorporated in the future to increase their accuracy.
本研究旨在比较盖伊评分系统和S.T.O.N.E.评分系统在预测经皮肾镜取石术(PCNL)结果方面的准确性。
获得伦理批准后,对2009年至2013年在一家三级结石中心接受PCNL治疗的患者的病历进行回顾性分析。计算盖伊评分系统和S.T.O.N.E.评分系统。进行回归分析和ROC曲线分析。
共回顾了185例PCNL手术。总体无结石率为71.9%,并发症发生率为16.2%。与有残余结石碎片的患者相比,无结石患者的盖伊分级(2.7对2;p<0.001)和S.T.O.N.E.评分(8.3对7.4;p=0.004)显著更低。逻辑回归分析表明,盖伊评分系统和S.T.O.N.E.评分系统均与无结石状态显著相关,OR分别为0.4(p<0.001)和0.7(p=0.001)。此外,两个评分系统均与估计失血量显著相关(p=0.01和p=0.005)。两个评分系统与手术时间(r=0.3,p<0.001和r=0.4,p<0.001)以及住院时间(r=0.2,p=0.001和r=0.3,p<0.001)之间均具有良好的相关性。然而,两个评分系统与并发症之间均无显著相关性(p=0.7和p=0.6)。盖伊评分系统和S.T.O.N.E.评分系统曲线下面积无显著差异(0.74[95%CI 0.66 - 0.82]对0.63[95%CI 0.54 - 0.72];p=0.06)。
盖伊评分系统和S.T.O.N.E.评分系统在预测PCNL术后无结石状态方面具有相当的准确性。未来可能需要纳入这两个评分系统中未包含的其他因素,以提高其准确性。