膜运输：内质网输出存在二元性。
Membrane trafficking: ER export encounters dualism.
作者信息
Barlowe Charles
机构信息
Department of Biochemistry, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
出版信息
Curr Biol. 2015 Feb 16;25(4):R151-3. doi: 10.1016/j.cub.2015.01.017.
PMID:25689910
Abstract
Cytoplasmic coat protein complexes perform central roles in sorting protein constituents within the endomembrane system. A new study reveals that the COPII coat operates through dual recognition of signals in a sorting receptor and its bound cargo to promote efficient export from the endoplasmic reticulum.
摘要
细胞质衣被蛋白复合物在内膜系统中对蛋白质成分进行分选时发挥着核心作用。一项新研究表明，COPII衣被通过对分选受体及其结合货物中的信号进行双重识别来促进从内质网的有效输出。
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