用蔗糖对脊髓灰质炎病毒3型减毒活疫苗株进行稳定化处理。
Stabilization of the attenuated poliovirus type 3 vaccine strain by sucrose.
作者信息
Srivastava A K
机构信息
Department of Virology, Nagasaki University, Japan.
出版信息
Acta Virol. 1989 Mar;33(2):188-90.
PMID:2569817
Abstract
Highly temperature-sensitive and attenuated poliovirus type 3, strain Leon 12a1b, was stabilized at 37 degrees C by 15% sucrose without 1 mol/1 MgCl2. The finding will contribute to poliovaccination in tropical countries.
摘要
高度温度敏感且减毒的3型脊髓灰质炎病毒，Leon 12a1b株，在不含1 mol/1 MgCl2的15%蔗糖溶液中于37摄氏度下实现了稳定。这一发现将有助于热带国家的脊髓灰质炎疫苗接种。
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