Kurahara Hiroshi, Maemura Kosei, Mataki Yuko, Sakoda Masahiko, Iino Satoshi, Hiwatashi Kiyokazu, Ishigami Sumiya, Ueno Shinichi, Shinchi Hiroyuki, Natsugoe Shoji
Hepatogastroenterology. 2014 Nov-Dec;61(136):2367-70.
BACKGROUND/AIMS: Pancreatic fistula (PF) is a major complication after distal pancreatectomy (DP). Popularization of laparoscopic surgery for DP has promoted the use of stapler for transection and closing of the pancreas.
We reviewed the medical records of 50 consecutive patients who underwent DP with stapler. Patients were divided into 2 groups: bare stapler (n=36) and reinforced stapler (n=14). We assessed the incidence of postoperative PF, systemic inflammatory response syndrome (SIRS), and intra-abdominal fluid collection on postoperative day 7.
The numbers of patients who developed grade A, grade B, and grade C PF were 17 (34%), 6 (12%), and 0, respectively. The incidence of postoperative PF was significantly lower in the reinforced stapler group (p=0.017). None of the patients in the reinforced stapler group developed grade B PF. Patients in the bare stapler group showed significantly higher incidence of postoperative SIRS (p=0.046), more extensive fluid collection (p=0.020), and longer postoperative hospital stay (p=0.023).
Decreased leakage of postoperative pancreatic juice into the abdominal cavity associated with the usage of the reinforced stapler may lead to reduced inflammatory reaction, low incidence of PF, and early hospital discharge.
背景/目的:胰瘘(PF)是胰体尾切除术(DP)后的主要并发症。DP腹腔镜手术的普及促进了吻合器在胰腺横断和闭合中的应用。
我们回顾了50例连续接受吻合器DP手术患者的病历。患者分为两组:裸吻合器组(n = 36)和加强吻合器组(n = 14)。我们评估了术后第7天术后PF、全身炎症反应综合征(SIRS)和腹腔积液的发生率。
发生A级、B级和C级PF的患者数量分别为17例(34%)、6例(12%)和0例。加强吻合器组术后PF的发生率显著较低(p = 0.017)。加强吻合器组无患者发生B级PF。裸吻合器组患者术后SIRS的发生率显著较高(p = 0.046),积液范围更广(p = 0.020),术后住院时间更长(p = 0.023)。
与使用加强吻合器相关的术后胰液腹腔渗漏减少可能导致炎症反应减轻、PF发生率降低和早期出院。