El Tayeb Marawan M, Knoedler John J, Krambeck Amy E, Paonessa Jessica E, Mellon Matthew J, Lingeman James E
Department of Urology, Indiana University School of Medicine, Indianapolis, IN.
Department of Urology, Mayo Clinic, Rochester, MN.
Urology. 2015 Apr;85(4):777-81. doi: 10.1016/j.urology.2014.12.044. Epub 2015 Feb 19.
To provide a contemporary look at vascular complications after percutaneous nephrolithotomy (PNL) with access performed solely by a urologist using fluoroscopic guidance.
A retrospective review of 2792 patients who had 3338 PNLs at Indiana University Health Methodist Hospital and Mayo Clinic Rochester was performed. Patients who experienced significant bleeding requiring diagnostic renal angiography and superselective embolization (SSE) were reviewed and compared with the overall database.
There were 15 patients (16 renal units) requiring renal angiography and SSE (0.48%). Mean time from PNL to bleeding was 7 days (range, 1-15 days) and to SSE was 9.6 days (range, 2-18 days). Mean drop in hemoglobin was 5.3 g/dL (range, 2-9 g/dL). Transfusion was needed in 9 patients (60%). There were no differences between the vascular complications group and the uneventful PNL group in mean age (55.06 vs 52.2 years; P = .519), UTI history (40% vs 38%; P = .92), mean operative time (125.8 vs 102.47 minutes; P = .192), the need for multiple access (18.75% vs 18%; P = .939), and access location. The vascular complications group had a lower stone burden than the uneventful PNL group (stones > 2 cm; 43.7% vs 74.03%; P = .014).
The incidence of vascular complications in this contemporary series is one of the lowest reported to date. At our centers, vascular bleeding complications appear to be a random and rare event after PNL as we were unable to identify any specific risk factors. Early SSE avoided the need for blood transfusion in many patients.
对仅由泌尿外科医生在荧光透视引导下进行经皮肾镜取石术(PNL)后的血管并发症进行当代观察。
对印第安纳大学健康卫理公会医院和梅奥诊所罗切斯特分院的2792例患者进行了3338次经皮肾镜取石术的回顾性研究。对经历严重出血需要诊断性肾血管造影和超选择性栓塞(SSE)的患者进行了回顾,并与整个数据库进行了比较。
有15例患者(16个肾单位)需要进行肾血管造影和超选择性栓塞(0.48%)。从经皮肾镜取石术到出血的平均时间为7天(范围1 - 15天),到超选择性栓塞的平均时间为9.6天(范围2 - 18天)。血红蛋白平均下降5.3 g/dL(范围2 - 9 g/dL)。9例患者(60%)需要输血。血管并发症组与经皮肾镜取石术顺利组在平均年龄(55.06岁对52.2岁;P = 0.519)、尿路感染史(40%对38%;P = 0.92)、平均手术时间(125.8分钟对102.47分钟;P = 0.192)、需要多次穿刺(18.75%对18%;P = 0.939)以及穿刺部位方面没有差异。血管并发症组的结石负荷低于经皮肾镜取石术顺利组(结石>2 cm;43.7%对74.03%;P = 0.014)。
在这个当代系列研究中,血管并发症的发生率是迄今为止报道的最低发生率之一。在我们的中心,经皮肾镜取石术后血管出血并发症似乎是随机且罕见的事件,因为我们无法识别任何特定的风险因素。早期超选择性栓塞避免了许多患者输血的需要。