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使用胶原海绵经耳道封闭鼓膜穿孔的临床研究

Clinical study of transcanal closure of tympanic membrane perforations using a collagen sponge.

作者信息

Tamae A, Komune S

机构信息

Department of Otolaryngology,Hamanomachi Hospital,Fukuoka,Japan.

Department of Otorhinolaryngology,Graduate School of Medical Sciences, Kyushu University,Fukuoka,Japan.

出版信息

J Laryngol Otol. 2015 Mar;129 Suppl 2:S21-6. doi: 10.1017/S0022215114002333.

Abstract

MATERIALS AND METHODS

We used an artificial dermis (Terdermis), which is an atero-collagen sponge covered with a sheet of silicon.

PATIENTS

Nineteen ears of 17 patients with perforation of the tympanic membrane under various conditions, including large and wet perforations, underwent operation using this collagen sponge.

RESULTS

The success rate of closure after the initial surgery was 8/19. The overall success rate of closure after initial and re-operation was 14/19. The success rate of closure was 12/14 for small-sized perforations, 1/4 for middle-sized perforations and 1/1 for a large-sized perforation. Middle- and large-sized perforations required multiple surgeries. The success rate of closure was 11/11 for dry perforations, 3/4 for perforations with light otorrhoea and 0/4 for perforations with extensive otorrhoea.

CONCLUSION

This surgery is a low-cost and minimally invasive surgery and has a high closure rate. This surgery is effective on small-sized, dry perforations although it can also close middle- and large-sized dry perforations.

摘要

材料与方法

我们使用了一种人工真皮(Terdermis),它是一种覆盖有硅片的前胶原海绵。

患者

17例鼓膜穿孔患者的19只耳朵,穿孔情况各异,包括大穿孔和湿穿孔,均使用这种胶原海绵进行了手术。

结果

初次手术后的闭合成功率为8/19。初次手术和再次手术后的总体闭合成功率为14/19。小穿孔的闭合成功率为12/14,中穿孔为1/4,大穿孔为1/1。中穿孔和大穿孔需要多次手术。干穿孔的闭合成功率为11/11,轻度耳漏穿孔为3/4,广泛耳漏穿孔为0/4。

结论

该手术是一种低成本、微创的手术,闭合率高。该手术对小的、干的穿孔有效,尽管它也能闭合中、大的干穿孔。

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