异基因造血细胞移植期间肠道微生物群的新影响：控制肠道，身体随之受益。
Emerging Influence of the Intestinal Microbiota during Allogeneic Hematopoietic Cell Transplantation: Control the Gut and the Body Will Follow.
作者信息
Docampo Melissa D, Auletta Jeffery J, Jenq Robert R
机构信息
Department of Immunology, Weill Cornell Graduate School of Medical Sciences, New York, New York.
Host Defense Program, Hematology/Oncology/BMT and Infectious Diseases, Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio.
出版信息
Biol Blood Marrow Transplant. 2015 Aug;21(8):1360-6. doi: 10.1016/j.bbmt.2015.02.016. Epub 2015 Feb 21.
The intestinal microbiota has many critical roles in maintaining gastrointestinal epithelial and gastrointestinal systemic immune homeostasis. This review provides insight into how allogeneic hematopoietic cell transplantation (HCT) and its associated complications and supportive care therapies affect the microbiota. Additionally, the review discusses how preservation and restoration of the microbiota might be advantageous in decreasing HCT-related morbidity and mortality.
肠道微生物群在维持胃肠道上皮和胃肠道系统免疫稳态方面具有许多关键作用。本综述深入探讨了异基因造血细胞移植（HCT）及其相关并发症和支持性护理疗法如何影响微生物群。此外，本综述还讨论了微生物群的保存和恢复在降低HCT相关发病率和死亡率方面可能具有的优势。
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