R-CHOP化疗对非霍奇金淋巴瘤患者肝脏及纵隔血池（18）F-FDG标准化摄取值的影响
Effect of R-CHOP chemotherapy on liver and mediastinal blood pool (18)F-FDG standardized uptake values in patients with non-Hodgkin's lymphoma.
作者信息
Kaya Bugra, Dostbil Zeki, Ismailoglu Murat, Tasdemir Bekir, Sahin Ozlem
机构信息
Necmettin Erbakan University, Meram Medical Faculty, Department of Nuclear Medicine, Konya, Turkey.
Dicle University, Medical Faculty, Department of Nuclear Medicine, Diyarbakir, Turkey.
出版信息
Clin Imaging. 2015 Jul-Aug;39(4):632-5. doi: 10.1016/j.clinimag.2015.02.006. Epub 2015 Feb 12.
AIM
We aimed to investigate the impact of chemotherapy on (18)F-FDG uptake in the liver and mediastinal blood pool (MBP) among patients with non-Hodgkin's lymphoma.
METHODS
Twenty-three patients with NHL underwent baseline, interim, and postchemotherapy (18)F-FDG PET/CT. SUVmax and SUVmean values of the liver and MBP at imaging time were compared statistically.
RESULTS
We did not find any significant differences between the liver and mediastinum SUVmean and SUVmax values (P>.05).
CONCLUSIONS
Our study demonstrates that the (18)F-FDG uptake in the liver and MBP are not significantly affected by R-CHOP chemotherapy in patients with NHL.
目的
我们旨在研究化疗对非霍奇金淋巴瘤患者肝脏和纵隔血池（MBP）中（18）F-FDG摄取的影响。
方法
23例非霍奇金淋巴瘤患者接受了基线、化疗中期和化疗后的（18）F-FDG PET/CT检查。对成像时肝脏和MBP的SUVmax和SUVmean值进行统计学比较。
结果
我们未发现肝脏和纵隔的SUVmean和SUVmax值之间存在任何显著差异（P>0.05）。
结论
我们的研究表明，NHL患者肝脏和MBP中的（18）F-FDG摄取不受R-CHOP化疗的显著影响。
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