成人神经发生：经验依赖变化的基础。
Adult neurogenesis: a substrate for experience-dependent change.
机构信息
Department of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Department of Psychology and Princeton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
出版信息
Trends Cogn Sci. 2015 Mar;19(3):151-61. doi: 10.1016/j.tics.2015.01.001. Epub 2015 Feb 21.
A rapidly growing body of literature indicates that adult neurogenesis in the hippocampus is sensitive to a variety of environmental factors. The effects of emotionally salient experiences, such as stress and physical exercise, have been characterized extensively with regard to both adult neurogenesis and behaviors associated with the hippocampus. Experience-dependent changes in the production and function of new neurons may serve as a means to fine-tune the hippocampus to the predicted environment. Here, we discuss this possibility along with the argument that more naturalistic experimental conditions may be a necessary step toward understanding the adaptive significance of neurons born in the adult brain.
越来越多的文献表明，海马体中的成人神经发生对各种环境因素敏感。情绪显著体验（如压力和体育锻炼）对成年神经发生和与海马体相关的行为的影响已经得到了广泛的描述。新神经元的产生和功能的经验依赖性变化可能是微调海马体以适应预测环境的一种手段。在这里，我们讨论了这种可能性，并认为更自然的实验条件可能是理解成年大脑中产生的神经元的适应意义的必要步骤。
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