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[Efficiency of pre-operative chemoradiotherapy in treating a case of advanced rectal cancer].

作者信息

Tamura Atsushi, Ami Katsunori, Watanabe Ayako, Hayasaka Junnosuke, Takagi Kentaro, Okamoto Eiko, Kitazume Akiko, Kondou Mayumi, Gokita Kentaro, Imai Kenichiro, Tei Shikofumi, Ando Masayuki, Arai Kuniyuki, Shibayama Takao

机构信息

Dept. of Gastroenterology, Tokyo Metropolitan Toshima Hospital.

出版信息

Gan To Kagaku Ryoho. 2014 Nov;41(12):1566-8.

Abstract

There is insufficient evidence for the pre-operative use of chemoradiotherapy (CRT) in treatment of advanced rectal cancers, and its efficiency and safety are unclear. However, it has recently been suggested that a new class of carcinostatic agents are more effective during preoperative CRT. Under the National Comprehensive Cancer Network (NCCN) guidelines, 5-FU and capecitabine have been recommended as the standard drugs for use during combination chemoradiotherapy. The Japanese Society for Cancer of Colon and Rectum (JSCCR) guidelines for 2014 also recommend the use of both drugs during preoperative CRT. We report a case of rectal cancer, which was successfully treated with radical resection and neoadjuvant chemoradiotherapy.

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