氰基丙烯酸酯封闭胰空肠吻合口后PET/CT出现假阳性结果。

False-Positive PET/CT After Cyanoacrylate Sealing of a Pancreaticojejunostomy.

作者信息

Belyaev Orlin, Munding Johanna, Tannapfel Andrea, Uhl Waldemar

机构信息

Department of Surgery, St. Josef Hospital, Ruhr University of Bochum, Gudrunstr. 56, 44791, Bochum, Germany,

出版信息

J Gastrointest Surg. 2015 May;19(5):984-5. doi: 10.1007/s11605-015-2780-9. Epub 2015 Mar 3.

DOI:10.1007/s11605-015-2780-9

PMID:25731826

Abstract

In 2013, a 68-year-old male had a pancreaticoduodenectomy for pancreatic cancer. The pancreaticojejunostomy was sealed with cyanoacrylate (Dermabond) to prevent postoperative pancreatic fistula. Local recurrence of malignancy at the anastomosis was suspected 18 months later in PET/CT. Surgical revision was performed and anastomosis resected. However, histology showed no tumor recurrence, but strong inflammation and foreign-body reaction towards Dermabond. The sealant caused false-positive PET/CT findings, so its use in oncologic surgery should be abandoned.

摘要

2013年，一名68岁男性因胰腺癌接受了胰十二指肠切除术。胰空肠吻合口用氰基丙烯酸酯（皮肤粘合剂）封闭，以预防术后胰瘘。18个月后，在PET/CT检查中怀疑吻合口处出现恶性肿瘤局部复发。遂进行手术翻修并切除吻合口。然而，组织学检查显示无肿瘤复发，但对皮肤粘合剂有强烈炎症和异物反应。该密封剂导致PET/CT出现假阳性结果，因此应放弃其在肿瘤外科手术中的使用。