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一种在改善血流和减少肋骨骨折之间实现有效权衡的机械胸部按压闭环控制器。

A mechanical chest compressor closed-loop controller with an effective trade-off between blood flow improvement and ribs fracture reduction.

作者信息

Zhang Guang, Wu Taihu, Song Zhenxing, Wang Haitao, Lu Hengzhi, Wang Yalin, Wang Dan, Chen Feng

机构信息

Institute of Medical Equipment, National Biological Protection Engineering Centre, No. 106, Wandong Road, Tianjin, China.

出版信息

Med Biol Eng Comput. 2015 Jun;53(6):487-97. doi: 10.1007/s11517-015-1258-y. Epub 2015 Mar 4.

Abstract

Chest compression (CC) is a significant emergency medical procedure for maintaining circulation during cardiac arrest. Although CC produces the necessary blood flow for patients with heart arrest, improperly deep CC will contribute significantly to the risk of chest injury. In this paper, an optimal CC closed-loop controller for a mechanical chest compressor (OCC-MCC) was developed to provide an effective trade-off between the benefit of improved blood perfusion and the risk of ribs fracture. The trade-off performance of the OCC-MCC during real automatic mechanical CCs was evaluated by comparing the OCC-MCC and the traditional mechanical CC method (TMCM) with a human circulation hardware model based on hardware simulations. A benefit factor (BF), risk factor (RF) and benefit versus risk index (BRI) were introduced in this paper for the comprehensive evaluation of risk and benefit. The OCC-MCC was developed using the LabVIEW control platform and the mechanical chest compressor (MCC) controller. PID control is also employed by MCC for effective compression depth regulation. In addition, the physiological parameters model for MCC was built based on a digital signal processor for hardware simulations. A comparison between the OCC-MCC and TMCM was then performed based on the simulation test platform which is composed of the MCC, LabVIEW control platform, physiological parameters model for MCC and the manikin. Compared with the TMCM, the OCC-MCC obtained a better trade-off and a higher BRI in seven out of a total of nine cases. With a higher mean value of cardiac output (1.35 L/min) and partial pressure of end-tidal CO2 (15.7 mmHg), the OCC-MCC obtained a larger blood flow and higher BF than TMCM (5.19 vs. 3.41) in six out of a total of nine cases. Although it is relatively difficult to maintain a stable CC depth when the chest is stiff, the OCC-MCC is still superior to the TMCM for performing safe and effective CC during CPR. The OCC-MCC is superior to the TMCM in performing safe and effective CC during CPR and can be incorporated into the current version of mechanical CC devices for high quality CPR, in both in-hospital and out-of-hospital CPR settings.

摘要

胸外按压(CC)是心脏骤停期间维持循环的一项重要急救医疗程序。尽管胸外按压能为心脏骤停患者产生必要的血流,但按压过深会显著增加胸部受伤的风险。本文开发了一种用于机械胸外按压装置的最优胸外按压闭环控制器(OCC-MCC),以在改善血液灌注的益处与肋骨骨折风险之间实现有效权衡。通过基于硬件模拟,将OCC-MCC与传统机械胸外按压方法(TMCM)在人体循环硬件模型上进行比较,评估了OCC-MCC在实际自动机械胸外按压过程中的权衡性能。本文引入了益处因子(BF)、风险因子(RF)和益险指数(BRI),用于全面评估风险和益处。OCC-MCC是使用LabVIEW控制平台和机械胸外按压装置(MCC)控制器开发的。MCC还采用PID控制来有效调节按压深度。此外,基于数字信号处理器构建了MCC的生理参数模型,用于硬件模拟。然后基于由MCC、LabVIEW控制平台、MCC的生理参数模型和人体模型组成的模拟测试平台,对OCC-MCC和TMCM进行了比较。与TMCM相比,在总共九个案例中的七个案例中,OCC-MCC获得了更好的权衡和更高的BRI。在总共九个案例中的六个案例中,OCC-MCC的心输出量平均值较高(1.35升/分钟),呼气末二氧化碳分压较高(15.7毫米汞柱),其血流和BF均大于TMCM(分别为5.19和3.41)。尽管在胸部僵硬时相对难以保持稳定的胸外按压深度,但在心肺复苏期间进行安全有效的胸外按压时,OCC-MCC仍优于TMCM。在心肺复苏期间进行安全有效的胸外按压时,OCC-MCC优于TMCM,可纳入当前版本用于高质量心肺复苏的机械胸外按压装置中,适用于院内和院外心肺复苏场景。

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