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慢性额窦炎的内镜治疗:前瞻性生活质量分析

Endoscopic Management of Chronic Frontal Sinusitis: Prospective Quality of Life Analysis.

作者信息

Askar Mohamed H, Gamea Ahmed, Tomoum Mohamed O, Elsherif Hossam S, Ebert Charles, Senior Brent A

机构信息

Tanta University, Otolaryngology/Head and Neck Surgery, Tanta, El-Gharbiya, Egypt.

Tanta University, Otolaryngology/Head and Neck Surgery, Tanta, El-Gharbiya, Egypt University of North Carolina at Chapel Hill, Otolaryngology/Head and Neck Surgery, Chapel Hill, NC, USA

出版信息

Ann Otol Rhinol Laryngol. 2015 Aug;124(8):638-48. doi: 10.1177/0003489415573959. Epub 2015 Mar 3.

Abstract

BACKGROUND

Previous studies of endoscopic frontal sinus surgery have been primarily retrospective and focused on symptom relief only.

OBJECTIVES

To prospectively assess the impact of endoscopic frontal sinus surgery on frontal sinus ostium patency and disease-specific quality of life as measured by the Rhinosinusitis Disability Index (RSDI).

STUDY DESIGN

A 60-patient cohort with chronic frontal sinusitis (100 diseased frontal sinuses) was prospectively evaluated using the RSDI, computed tomography (CT) imaging, and endoscopic examination. Image-guided endoscopic frontal sinusotomy (Draf 2a) was performed in each case. Patients were assessed with RSDI and endoscopic assessment at least 6 months postoperatively.

RESULTS

At a mean follow-up of 10 months, endoscopic assessment revealed patent frontal recesses in 90 of 100 frontal sinuses (90%), with significant improvement in the total RSDI score (41.98 ± 26.48 preoperatively to 17.15 ± 15.66 postoperatively) as well as each of its physical, emotional, and functional subscales from 16.3 ± 9.03, 12.23 ± 10.55, 13.45 ± 9.59 preoperatively to 5.95 ± 5.71, 5.55 ± 5.66, 5.65 ± 5.72 postoperatively, respectively. Similar improvement was seen in patients with asthma, polyps, and those undergoing revision sinus surgeries.

CONCLUSIONS

With frontal recess mucosal preservation and meticulous postoperative endoscopic surveillance, endoscopic frontal sinusotomy results in high rates of frontal sinus ostium patency with significant improvement in quality of life.

摘要

背景

以往关于内镜下额窦手术的研究主要是回顾性的,且仅关注症状缓解情况。

目的

前瞻性评估内镜下额窦手术对额窦开口通畅度以及通过鼻窦炎残疾指数(RSDI)衡量的疾病特异性生活质量的影响。

研究设计

采用RSDI、计算机断层扫描(CT)成像和内镜检查对60例慢性额窦炎患者(100个患病额窦)进行前瞻性评估。每例患者均接受图像引导下的内镜额窦切开术(Draf 2a)。术后至少6个月对患者进行RSDI评估和内镜检查。

结果

平均随访10个月时,内镜检查显示100个额窦中有90个(90%)额隐窝通畅,RSDI总分(术前41.98±26.48,术后17.15±15.66)以及其身体、情感和功能各子量表均有显著改善,术前分别为16.3±9.03、12.23±10.55、13.45±9.59,术后分别为5.95±5.71、5.55±5.66、5.65±5.72。哮喘患者、有息肉的患者以及接受鼻窦翻修手术的患者也有类似改善。

结论

通过保留额隐窝黏膜并进行细致的术后内镜监测,内镜下额窦切开术可使额窦开口通畅率较高,并显著改善生活质量。

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