Waljee Jennifer, Zhong Lin, Baser Onur, Yuce Huseyin, Fox David A, Chung Kevin C
Section of Plastic Surgery, Department of Surgery (J.W., L.Z., and K.C.C.), and Department of Internal Medicine (O.B. and D.A.F.), University of Michigan Health System, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5340. E-mail address for K.C. Chung:
Department of Mathematics, New York City College of Technology, 300 Jay Street, N826, Brooklyn, NY 11201.
J Bone Joint Surg Am. 2015 Mar 4;97(5):403-10. doi: 10.2106/JBJS.N.00802.
BACKGROUND: For elderly patients with rheumatoid arthritis, aggressive immunosuppression can be difficult to tolerate, and surgery remains an important treatment option for joint pain and deformity. We sought to examine the epidemiology of surgical reconstruction for rheumatoid arthritis among older individuals who were newly diagnosed with the disorder. METHODS: We identified a 5% random sample of Medicare beneficiaries (sixty-six years of age and older) newly diagnosed with rheumatoid arthritis from 2000 to 2005, and followed these patients longitudinally for a mean of 4.6 years. We used univariate analysis to compare the time from the diagnosis of rheumatoid arthritis to the first operation among the 360 patients who underwent surgery during the study period. RESULTS: In our study cohort, 589 procedures were performed among 360 patients, and 132 patients (37%) underwent multiple procedures. The rate of upper extremity reconstruction was 0.9%, the rate of lower extremity reconstruction was 1.2%, and knee arthroplasty was the most common procedure performed initially (31%) and overall (29%). Upper extremity procedures were performed sooner than lower extremity procedures (fourteen versus twenty-five months; p = 0.02). In multivariable analysis, surgery rates declined with age for upper and lower extremity procedures (p < 0.001). CONCLUSIONS: Knee replacement remains the most common initial procedure among patients with rheumatoid arthritis. However, upper extremity procedures are performed earlier than lower extremity procedures. Understanding the patient and provider factors that underlie variation in procedure rates can inform future strategies to improve the delivery of care to patients with rheumatoid arthritis.
背景:对于老年类风湿关节炎患者而言,积极的免疫抑制治疗可能难以耐受,而手术仍是治疗关节疼痛和畸形的重要选择。我们试图研究新诊断为类风湿关节炎的老年患者行外科重建手术的流行病学情况。 方法:我们从2000年至2005年新诊断为类风湿关节炎的医疗保险受益人(66岁及以上)中抽取5%的随机样本,并对这些患者进行平均4.6年的纵向随访。我们采用单因素分析比较了研究期间接受手术的360例患者从类风湿关节炎诊断到首次手术的时间。 结果:在我们的研究队列中,360例患者共进行了589次手术,132例患者(37%)接受了多次手术。上肢重建率为0.9%,下肢重建率为1.2%,膝关节置换术是最初(31%)和总体(29%)最常进行的手术。上肢手术比下肢手术进行得更早(分别为14个月和25个月;p = 0.02)。在多变量分析中,上肢和下肢手术的手术率均随年龄下降(p < 0.001)。 结论:膝关节置换术仍然是类风湿关节炎患者最常见的初始手术。然而,上肢手术比下肢手术进行得更早。了解手术率差异背后的患者和提供者因素可为未来改善类风湿关节炎患者护理提供策略提供参考。
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