Einspieler Christa, Yang Hong, Bartl-Pokorny Katrin D, Chi Xia, Zang Fei-Fei, Marschik Peter B, Guzzetta Andrea, Ferrari Fabrizio, Bos Arend F, Cioni Giovanni
Research Unit iDN, Interdisciplinary Developmental Neuroscience, Institute of Physiology, Center for Physiological Medicine, Medical University of Graz, Austria.
Department of Rehabilitation, Children's Hospital of Fudan University, Shanghai, PR China.
Early Hum Dev. 2015 Apr;91(4):247-52. doi: 10.1016/j.earlhumdev.2015.02.003. Epub 2015 Mar 4.
Infants with normal fidgety movements at 3 to 5 months after term are very likely to show neurologically normal development, while the absence of fidgety movements is an early marker for an adverse neurological outcome, mainly cerebral palsy (CP). The clinical significance of so-called sporadic fidgety movements (i.e., fidgety movements occur isolated in a few body parts and are of 1- to 3-second-duration) is not yet known.
Our objective was to determine whether infants who had developed CP and had sporadic fidgety movements have a better outcome than infants who did not have fidgety movements.
Longitudinal study. Retrospective analysis of prospectively collected data.
61 infants who developed CP (46 male, 15 female; 29 infants born preterm; videoed for the assessment of movements and postures at 9 to 16 weeks post-term age).
The Gross Motor Function Classification System (GMFCS) was applied at 3 to 5 years of age.
There was no difference between children diagnosed with CP who had sporadic fidgety movements at 9 to 16 weeks post-term age (n = 9) and those who never developed fidgety movements (n = 50) with regard to their functional mobility and activity limitation at 3 to 5 years of age. One infant had normal FMs and developed unilateral CP, GMFCS Level I; the remaining infant had abnormal FMs and developed bilateral CP, GMFCS Level II.
There is no evidence that the occurrence of occasional isolated fidgety bursts indicates a milder type of CP.
足月出生后3至5个月出现正常不安运动的婴儿很可能神经发育正常，而缺乏不安运动是不良神经结局的早期标志，主要是脑瘫（CP）。所谓的散发性不安运动（即不安运动孤立地出现在身体的几个部位，持续时间为1至3秒）的临床意义尚不清楚。
我们的目的是确定已患脑瘫且有散发性不安运动的婴儿是否比没有不安运动的婴儿预后更好。
纵向研究。对前瞻性收集的数据进行回顾性分析。
61名患脑瘫的婴儿（46名男性，15名女性；29名早产婴儿；在足月后9至16周拍摄视频以评估运动和姿势）。
在3至5岁时应用粗大运动功能分类系统（GMFCS）进行评估。
在足月后9至16周有散发性不安运动的脑瘫患儿（n = 9）与从未出现不安运动的患儿（n = 50）在3至5岁时的功能活动能力和活动受限方面没有差异。一名婴儿不安运动正常，患单侧脑瘫，GMFCS I级；其余婴儿不安运动异常，患双侧脑瘫，GMFCS II级。
没有证据表明偶尔出现的孤立性不安运动发作意味着脑瘫类型较轻。
