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儿童强迫症中的转换性强迫观念:临床特征及对认知行为疗法的治疗反应

Transformation obsessions in paediatric obsessive-compulsive disorder: Clinical characteristics and treatment response to cognitive behaviour therapy.

作者信息

Monzani B, Jassi A, Heyman I, Turner C, Volz C, Krebs G

机构信息

Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, UK.

Institute of Psychiatry, Psychology & Neuroscience, King's College London, London SE5 8AF, UK; OCD & Related Disorders Clinic for Young People, South London and Maudsley NHS Foundation Trust, London SE5 8AZ, UK.

出版信息

J Behav Ther Exp Psychiatry. 2015 Sep;48:75-81. doi: 10.1016/j.jbtep.2015.02.004. Epub 2015 Feb 19.

Abstract

BACKGROUND AND OBJECTIVES

Transformation obsessions denote an under-reported symptom of Obsessive Compulsive Disorder (OCD), characterised by an excessive fear of turning into another person/object or acquiring unwanted characteristics. Relative to other OCD symptoms, little is known about the clinical presentation of transformation obsessions. The study aims to examine the clinical correlates and treatment prognosis of transformation obsessions in a paediatric OCD sample.

METHODS

The sample consisted of 346 youths with a primary diagnosis of OCD. Patients with and without transformation obsessions were compared in terms of demographic and clinical characteristics, and CBT outcomes.

RESULTS

10% of the sample endorsed transformation obsessions. Patients with transformation obsessions were more likely to be boys, to be on augmented medication regimes, and to present with more severe obsessions at assessment. A factor analysis identified four major OCD symptom clusters, with transformation obsessions loading on a 'forbidden thoughts' factor alongside aggressive, sexual, and religious obsessions. No group differences in treatment outcomes were observed.

LIMITATIONS

Limitations include the cross-sectional and retrospective nature of the study, the representativeness of our sample, and use of concomitant medication, among others.

CONCLUSIONS

The study provides the first empirical evidence regarding phenomenological similarities and differences between paediatric OCD patients presenting with and without transformation obsessions. The findings suggest that transformation obsessions are best conceptualised as related to 'forbidden' obsessions and respond to exposure-based CBT.

摘要

背景与目的

变形强迫观念是强迫症(OCD)中一种报道较少的症状,其特征是过度害怕变成另一个人/物体或获得 unwanted 特征。相对于其他强迫症症状,人们对变形强迫观念的临床表现知之甚少。本研究旨在探讨儿科强迫症样本中变形强迫观念的临床相关性和治疗预后。

方法

样本包括 346 名初步诊断为强迫症的青少年。对有和没有变形强迫观念的患者在人口统计学和临床特征以及认知行为疗法(CBT)结果方面进行了比较。

结果

10%的样本认可有变形强迫观念。有变形强迫观念的患者更可能是男孩,更可能采用强化药物治疗方案,并且在评估时表现出更严重的强迫观念。一项因素分析确定了四个主要的强迫症症状群,变形强迫观念与攻击性、性和宗教强迫观念一起归入“禁忌思想”因素。未观察到治疗结果的组间差异。

局限性

局限性包括研究的横断面和回顾性性质、我们样本的代表性以及同时使用药物等。

结论

该研究提供了关于有和没有变形强迫观念的儿科强迫症患者之间现象学异同的首个实证证据。研究结果表明,变形强迫观念最好被概念化为与“禁忌”强迫观念相关,并对基于暴露的认知行为疗法有反应。

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