Transcriptome changes induced by chronic psychosocial/environmental or neuroendocrine stressors reveal a selective cellular vulnerability of cortical somatostatin (SST) neurons, compared with pyramidal (PYR) neurons.
作者信息
Lin L C, Sibille E
机构信息
Department of Psychiatry, Translational Neuroscience Program, Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA.
1] Department of Psychiatry, Translational Neuroscience Program, Center for Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA [2] Departments of Psychiatry, Pharmacology and Toxicology, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of Toronto, Toronto, ON, Canada.
出版信息
Mol Psychiatry. 2015 Mar;20(3):285. doi: 10.1038/mp.2015.24.
Abstract
摘要
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Transcriptome changes induced by chronic psychosocial/environmental or neuroendocrine stressors reveal a selective cellular vulnerability of cortical somatostatin (SST) neurons, compared with pyramidal (PYR) neurons.与锥体神经元相比，慢性心理社会/环境或神经内分泌应激源诱导的转录组变化揭示了皮质生长抑素（SST）神经元具有选择性细胞易损性。
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